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CHEBI:3750 - clofibrate

Default Structure
ChEBI IDCHEBI:3750
ChEBI Nameclofibrate
Stars
DefinitionThe ethyl ester of clofibric acid.
Last Modified20 September 2021
DownloadsMolfile
FormulaC12H15ClO3
Net Charge0
Average Mass242.702
Monoisotopic Mass242.07097
SMILESCCOC(=O)C(C)(C)Oc1ccc(Cl)cc1
InChIInChI=1S/C12H15ClO3/c1-4-15-11(14)12(2,3)16-10-7-5-9(13)6-8-10/h5-8H,4H2,1-3H3
InChIKeyKNHUKKLJHYUCFP-UHFFFAOYSA-N
Wikipedia
Roles Classification
Biological Role:
PPARalpha agonist  A PPAR modulator which activates the peroxisome proliferator-activated receptor-α.
Applications:
anticholesteremic drug  A substance used to lower plasma cholesterol levels.
antilipemic drug  A substance used to treat hyperlipidemia (an excess of lipids in the blood).
cardiovascular drug  A drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume.
geroprotector  Any compound that supports healthy aging, slows the biological aging process, or extends lifespan.
ChEBI Ontology
Outgoing Relation(s)
clofibrate (CHEBI:3750) has functional parent clofibric acid (CHEBI:34648)
clofibrate (CHEBI:3750) has role anticholesteremic drug (CHEBI:35821)
clofibrate (CHEBI:3750) has role antilipemic drug (CHEBI:35679)
clofibrate (CHEBI:3750) has role cardiovascular drug (CHEBI:35554)
clofibrate (CHEBI:3750) has role geroprotector (CHEBI:176497)
clofibrate (CHEBI:3750) has role PPARα agonist (CHEBI:70782)
clofibrate (CHEBI:3750) is a aromatic ether (CHEBI:35618)
clofibrate (CHEBI:3750) is a ethyl ester (CHEBI:23990)
clofibrate (CHEBI:3750) is a monochlorobenzenes (CHEBI:83403)
IUPAC Name 
ethyl 2-(4-chlorophenoxy)-2-methylpropanoate
INNs  Source
clofibrateChemIDplus
clofibratoChemIDplus
clofibratumChemIDplus
Synonyms  Source
2-(4-Chlorophenoxy)-2-methylpropanoic acid ethyl esterChemIDplus
2-(p-Chlorophenoxy)-2-methylpropionic acid ethyl esterChemIDplus
alpha-(p-Chlorophenoxy)isobutyric acid, ethyl esterChemIDplus
alpha-p-Chlorophenoxyisobutyryl ethyl esterChemIDplus
AY-61123ChEMBL
ChlorfenisateChEMBL
Brand Names  Source
AtromidChEMBL
Atromid-SKEGG DRUG
ELPIDrugBank
LipofactonDrugBank
Manual XrefsDatabases
2694ChemSpider
694DrugCentral
C06916KEGG COMPOUND
ClofibrateWikipedia
D00279KEGG DRUG
DB00636DrugBank
GB860303Patent
HMDB0014774HMDB
LSM-2996LINCS
US3262850Patent
Registry NumbersSources
Beilstein:1913459Beilstein
CAS:637-07-0ChemIDplus
CAS:637-07-0NIST Chemistry WebBook
Citations