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CHEBI:37447 - meso-tetrakis(N-methyl-4-pyridyl)porphine(4+)

ChEBI IDCHEBI:37447
ChEBI Namemeso-tetrakis(N-methyl-4-pyridyl)porphine(4+)
Stars
ASCII Namemeso-tetrakis(N-methyl-4-pyridyl)porphine(4+)
DefinitionAn organic cation that is porphyrin bearing four 1-methylpyridinium-4-yl groups at the 5-, 10-, 15- and 20-positions.
Secondary ChEBI IDCHEBI:78041
Last Modified2 April 2014
SubmitterKirill Degtyarenko, Steve
DownloadsMolfile
FormulaC44H38N8
Net Charge+4
Average Mass678.844
Monoisotopic Mass678.31975
SMILESC[n+]1ccc(-c2c3ccc(n3)c(-c3cc[n+](C)cc3)c3nc(c(-c4cc[n+](C)cc4)c4ccc(n4)c(-c4cc[n+](C)cc4)c4nc2C=C4)C=C3)cc1
InChIInChI=1S/C44H37N8/c1-49-21-13-29(14-22-49)41-33-5-7-35(45-33)42(30-15-23-50(2)24-16-30)37-9-11-39(47-37)44(32-19-27-52(4)28-20-32)40-12-10-38(48-40)43(36-8-6-34(41)46-36)31-17-25-51(3)26-18-31/h5-28H,1-4H3,(H,45,46,47,48)/q+3/p+1/b41-33-,41-34-,42-35-,42-37-,43-36-,43-38-,44-39-,44-40-
InChIKeyABCGFHPGHXSVKI-LWQDQPMZSA-O
Roles Classification
Biological Role:
EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor  A DNA polymerase inhibitor that interferes with the activity of reverse transcriptase, EC 2.7.7.49, a viral DNA polymerase enzyme that retroviruses need in order to reproduce.
Applications:
antineoplastic agent  A substance that inhibits or prevents the proliferation of neoplasms.
photosensitizing agent  A chemical compound that can be excited by light of a specific wavelength and subsequently transfer energy to a chosen reactant. This is commonly molecular oxygen within a cancer tissue, which is converted to (highly rective) singlet state oxygen. This rapidly reacts with any nearby biomolecules, ultimately killing the cancer cells.
angiogenesis inhibitor  An agent and endogenous substances that antagonize or inhibit the development of new blood vessels.
ChEBI Ontology
Outgoing Relation(s)
meso-tetrakis(N-methyl-4-pyridyl)porphine(4+) (CHEBI:37447) has parent hydride porphyrin (CHEBI:8337)
meso-tetrakis(N-methyl-4-pyridyl)porphine(4+) (CHEBI:37447) has role angiogenesis inhibitor (CHEBI:48422)
meso-tetrakis(N-methyl-4-pyridyl)porphine(4+) (CHEBI:37447) has role antineoplastic agent (CHEBI:35610)
meso-tetrakis(N-methyl-4-pyridyl)porphine(4+) (CHEBI:37447) has role EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor (CHEBI:59897)
meso-tetrakis(N-methyl-4-pyridyl)porphine(4+) (CHEBI:37447) has role photosensitizing agent (CHEBI:47868)
meso-tetrakis(N-methyl-4-pyridyl)porphine(4+) (CHEBI:37447) is a organic cation (CHEBI:25697)
Incoming Relation(s)
meso-tetrakis(N-methyl-4-pyridyl)porphine tetrakis(p-toluenesulfonate) (CHEBI:78039) has part meso-tetrakis(N-methyl-4-pyridyl)porphine(4+) (CHEBI:37447)
IUPAC Names 
5,10,15,20-tetrakis(1-methylpyridinium-4-yl)porphyrin
4,4',4'',4'''-porphyrin-5,10,15,20-tetrayltetrakis(1-methylpyridinium)
Synonyms  Source
tetra(4-N-methylpyridyl)porphineChEBI
meso-Tetrakis(2-N-methylpyridyl)porphineChemIDplus
Tetrakis(N-methyl-4-pyridino)porphineChemIDplus
meso-Tetrakis(N-methyl-4-pyridinium)phenyl porphyrinChemIDplus
Mesotetra(4-N-methylpyridyl)porphineChemIDplus
meso-tetrakis(N-methyl-4-pyridyl)porphineChEBI
Registry NumbersSources
Gmelin:87183Gmelin
Reaxys:3586693Reaxys
CAS:38673-65-3ChemIDplus
Citations