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CHEBI:364453 - carprofen
| Formula | C15H12ClNO2 |
| Net Charge | 0 |
| Average Mass | 273.719 |
| Monoisotopic Mass | 273.05566 |
| SMILES | CC(C(=O)O)c1ccc2c(c1)nc1ccc(Cl)cc12 |
| InChI | InChI=1S/C15H12ClNO2/c1-8(15(18)19)9-2-4-11-12-7-10(16)3-5-13(12)17-14(11)6-9/h2-8,17H,1H3,(H,18,19) |
| InChIKey | PUXBGTOOZJQSKH-UHFFFAOYSA-N |
| Wikipedia |
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| Roles Classification |
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| Biological Role: | EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor A compound or agent that combines with cyclooxygenases (EC 1.14.99.1) and thereby prevents its substrate-enzyme combination with arachidonic acid and the formation of icosanoids, prostaglandins, and thromboxanes. |
| Applications: | photosensitizing agent A chemical compound that can be excited by light of a specific wavelength and subsequently transfer energy to a chosen reactant. This is commonly molecular oxygen within a cancer tissue, which is converted to (highly rective) singlet state oxygen. This rapidly reacts with any nearby biomolecules, ultimately killing the cancer cells. non-steroidal anti-inflammatory drug An anti-inflammatory drug that is not a steroid. In addition to anti-inflammatory actions, non-steroidal anti-inflammatory drugs have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| carprofen (CHEBI:364453) has role EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor (CHEBI:35544) |
| carprofen (CHEBI:364453) has role non-steroidal anti-inflammatory drug (CHEBI:35475) |
| carprofen (CHEBI:364453) has role photosensitizing agent (CHEBI:47868) |
| carprofen (CHEBI:364453) is a carbazoles (CHEBI:48513) |
| carprofen (CHEBI:364453) is a organochlorine compound (CHEBI:36683) |
| Incoming Relation(s) |
| (R)-carprofen (CHEBI:59206) is a carprofen (CHEBI:364453) |
| (S)-carprofen (CHEBI:59207) is a carprofen (CHEBI:364453) |
| IUPAC Name |
|---|
| 2-(6-chloro-9H-carbazol-2-yl)propanoic acid |
| INNs | Source |
|---|---|
| carprofen | ChemIDplus |
| carprofene | ChemIDplus |
| carprofenum | ChemIDplus |
| carprofeno | ChemIDplus |
| Synonyms | Source |
|---|---|
| (+/-)-2-(3-chloro-9H-carbazol-7-yl)propanoic acid | ChEMBL |
| 2-(6-Chloro-9H-carbazol-2-yl)-propionic acid | ChEMBL |
| (±)-6-chloro-α-methylcarbazole-2-acetic acid | ChemIDplus |
| 6-chloro-α-methyl-9H-carbazole-2-acetic acid | ChEBI |
| Citations |
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