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CHEBI:3619 - chlormezanone

ChEBI IDCHEBI:3619
ChEBI Namechlormezanone
Stars
DefinitionA 1,3-thiazine that is 1,3-thiazinan-4-one S,S-dioxide in which a hydrogen at position 2 is substituted by a 4-chlorophenyl group and the hydrogen attached to the nitrogen is substituted by methyl. A non-benzodiazepine muscle relaxant, it was used in the management of anxiety and in the treatment of muscle spasms until being discontinued worldwide by its manufacturer in 1996, due to rare but serious cutaneous reactions.
Last Modified20 June 2018
DownloadsMolfile
FormulaC11H12ClNO3S
Net Charge0
Average Mass273.741
Monoisotopic Mass273.02264
SMILESCN1C(=O)CCS(=O)(=O)C1c1ccc(Cl)cc1
InChIInChI=1S/C11H12ClNO3S/c1-13-10(14)6-7-17(15,16)11(13)8-2-4-9(12)5-3-8/h2-5,11H,6-7H2,1H3
InChIKeyWEQAYVWKMWHEJO-UHFFFAOYSA-N
Wikipedia
Roles Classification
Applications:
antipsychotic agent  Antipsychotic drugs are agents that control agitated psychotic behaviour, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect.
anxiolytic drug  Anxiolytic drugs are agents that alleviate anxiety, tension, and anxiety disorders, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions.
muscle relaxant  A drug used to produce muscle relaxation (excepting neuromuscular blocking agents). Its primary clinical and therapeutic use is the treatment of muscle spasm and immobility associated with strains, sprains, and injuries of the back and, to a lesser degree, injuries to the neck. Also used for the treatment of a variety of clinical conditions that have in common only the presence of skeletal muscle hyperactivity, for example, the muscle spasms that can occur in multiple sclerosis.
ChEBI Ontology
Outgoing Relation(s)
chlormezanone (CHEBI:3619) has role antipsychotic agent (CHEBI:35476)
chlormezanone (CHEBI:3619) has role anxiolytic drug (CHEBI:35474)
chlormezanone (CHEBI:3619) has role muscle relaxant (CHEBI:51371)
chlormezanone (CHEBI:3619) is a 1,3-thiazine (CHEBI:46975)
chlormezanone (CHEBI:3619) is a lactam (CHEBI:24995)
chlormezanone (CHEBI:3619) is a monochlorobenzenes (CHEBI:83403)
chlormezanone (CHEBI:3619) is a sulfone (CHEBI:35850)
Incoming Relation(s)
(R)-chlormezanone (CHEBI:59467) is a chlormezanone (CHEBI:3619)
(S)-chlormezanone (CHEBI:59468) is a chlormezanone (CHEBI:3619)
IUPAC Name 
2-(4-chlorophenyl)-3-methyl-1,3-thiazinan-4-one 1,1-dioxide
INNs  Source
chlormezanonaChemIDplus
chlormezanonumChemIDplus
chlormezanoneChemIDplus
chlormézanoneWHO MedNet
Synonyms  Source
2-(p-chlorphenyl)-3-methyl-1,3-perhydrothiazin-4-on-1,1-dioxideChemIDplus
(±)-chlormezanoneChemIDplus
chlormethazanoneChemIDplus
2-(p-chlorophenyl)tetrahydro-3-methyl-4H-1,3-thiazin-4-one 1,1-dioxideChemIDplus
Manual XrefsDatabases
DB01178DrugBank
D00268KEGG DRUG
GB815203Patent
ChlormezanoneWikipedia
LSM-4356LINCS
603DrugCentral
Registry NumbersSources
Reaxys:23033Reaxys
CAS:80-77-3KEGG DRUG
CAS:80-77-3ChemIDplus
Citations