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CHEBI:331697 - atomoxetine hydrochloride

ChEBI IDCHEBI:331697
ChEBI Nameatomoxetine hydrochloride
Stars
DefinitionThe hydrochloride salt of atomoxetine.
Last Modified11 January 2010
DownloadsMolfile
FormulaC17H21NO.HCl
Net Charge0
Average Mass291.822
Monoisotopic Mass291.13899
SMILESCNCC[C@@H](Oc1ccccc1C)c1ccccc1.Cl
InChIInChI=1S/C17H21NO.ClH/c1-14-8-6-7-11-16(14)19-17(12-13-18-2)15-9-4-3-5-10-15;/h3-11,17-18H,12-13H2,1-2H3;1H/t17-;/m1./s1
InChIKeyLUCXVPAZUDVVBT-UNTBIKODSA-N
Roles Classification
Biological Role:
adrenergic uptake inhibitor  Adrenergic uptake inhibitors are drugs that block the transport of adrenergic transmitters into axon terminals or into storage vesicles within terminals. The tricyclic antidepressants and amphetamines are among the therapeutically important drugs that may act via inhibition of adrenergic transport. Many of these drugs also block transport of serotonin.
Applications:
adrenergic uptake inhibitor  Adrenergic uptake inhibitors are drugs that block the transport of adrenergic transmitters into axon terminals or into storage vesicles within terminals. The tricyclic antidepressants and amphetamines are among the therapeutically important drugs that may act via inhibition of adrenergic transport. Many of these drugs also block transport of serotonin.
antidepressant  Antidepressants are mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions.
ChEBI Ontology
Outgoing Relation(s)
atomoxetine hydrochloride (CHEBI:331697) has part atomoxetine (CHEBI:127342)
atomoxetine hydrochloride (CHEBI:331697) has role adrenergic uptake inhibitor (CHEBI:35640)
atomoxetine hydrochloride (CHEBI:331697) has role antidepressant (CHEBI:35469)
atomoxetine hydrochloride (CHEBI:331697) is a hydrochloride (CHEBI:36807)
IUPAC Name 
(3R)-N-methyl-3-(2-methylphenoxy)-3-phenylpropan-1-amine hydrochloride
INNs  Source
tomoxetineDrugBank
atomoxetineChEBI
Synonyms  Source
Tomoxetine hydrochlorideKEGG DRUG
(-)-N-Methyl-3-phenyl-3-(o-tolyloxy)propylamine hydrochlorideChemIDplus
(R)-(-)-Tomoxetine hydrochlorideChemIDplus
(R)-Tomoxetine hydrochlorideChemIDplus
Atomoxetine HClChemIDplus
Manual XrefsDatabases
D02574KEGG DRUG
DB00289DrugBank
Registry NumbersSources
Beilstein:5318974Beilstein
CAS:82248-59-7KEGG DRUG
CAS:82248-59-7DrugBank
CAS:82248-59-7ChemIDplus