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CHEBI:127342 - atomoxetine
| Formula | C17H21NO |
| Net Charge | 0 |
| Average Mass | 255.361 |
| Monoisotopic Mass | 255.16231 |
| SMILES | CNCC[C@@H](Oc1ccccc1C)c1ccccc1 |
| InChI | InChI=1S/C17H21NO/c1-14-8-6-7-11-16(14)19-17(12-13-18-2)15-9-4-3-5-10-15/h3-11,17-18H,12-13H2,1-2H3/t17-/m1/s1 |
| InChIKey | VHGCDTVCOLNTBX-QGZVFWFLSA-N |
| Wikipedia |
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| Roles Classification |
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| Chemical Roles: | environmental contaminant Any minor or unwanted substance introduced into the environment that can have undesired effects. Bronsted base A molecular entity capable of accepting a hydron from a donor (Brønsted acid). |
| Biological Roles: | adrenergic uptake inhibitor Adrenergic uptake inhibitors are drugs that block the transport of adrenergic transmitters into axon terminals or into storage vesicles within terminals. The tricyclic antidepressants and amphetamines are among the therapeutically important drugs that may act via inhibition of adrenergic transport. Many of these drugs also block transport of serotonin. xenobiotic A xenobiotic (Greek, xenos "foreign"; bios "life") is a compound that is foreign to a living organism. Principal xenobiotics include: drugs, carcinogens and various compounds that have been introduced into the environment by artificial means. |
| Applications: | vasoconstrictor agent Drug used to cause constriction of the blood vessels. adrenergic uptake inhibitor Adrenergic uptake inhibitors are drugs that block the transport of adrenergic transmitters into axon terminals or into storage vesicles within terminals. The tricyclic antidepressants and amphetamines are among the therapeutically important drugs that may act via inhibition of adrenergic transport. Many of these drugs also block transport of serotonin. antiparkinson drug A drug used in the treatment of Parkinson's disease. hypoglycemic agent A drug which lowers the blood glucose level. antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. antipsychotic agent Antipsychotic drugs are agents that control agitated psychotic behaviour, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect. antidepressant Antidepressants are mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| atomoxetine (CHEBI:127342) has role adrenergic uptake inhibitor (CHEBI:35640) |
| atomoxetine (CHEBI:127342) has role antidepressant (CHEBI:35469) |
| atomoxetine (CHEBI:127342) has role antineoplastic agent (CHEBI:35610) |
| atomoxetine (CHEBI:127342) has role antiparkinson drug (CHEBI:48407) |
| atomoxetine (CHEBI:127342) has role antipsychotic agent (CHEBI:35476) |
| atomoxetine (CHEBI:127342) has role environmental contaminant (CHEBI:78298) |
| atomoxetine (CHEBI:127342) has role hypoglycemic agent (CHEBI:35526) |
| atomoxetine (CHEBI:127342) has role vasoconstrictor agent (CHEBI:50514) |
| atomoxetine (CHEBI:127342) has role xenobiotic (CHEBI:35703) |
| atomoxetine (CHEBI:127342) is a aromatic ether (CHEBI:35618) |
| atomoxetine (CHEBI:127342) is a secondary amino compound (CHEBI:50995) |
| atomoxetine (CHEBI:127342) is a toluenes (CHEBI:27024) |
| Incoming Relation(s) |
| atomoxetine hydrochloride (CHEBI:331697) has part atomoxetine (CHEBI:127342) |
| IUPAC Name |
|---|
| (3R)-N-methyl-3-(2-methylphenoxy)-3-phenylpropan-1-amine |
| INNs | Source |
|---|---|
| atomoxetina | WHO MedNet |
| atomoxetine | KEGG DRUG |
| tomoxetine | DrugBank |
| Synonyms | Source |
|---|---|
| Tomoxetina | DrugBank |
| (-)-Tomoxetine | ChEBI |
| Tomoxetinum | DrugBank |
| Brand Names | Source |
|---|---|
| Atomoxetine component of ad-109 | ChEMBL |
| Atomoxetine component of ad109 | ChEMBL |
| Atomoxetine component of ad-313 | ChEMBL |
| Atomoxetine component of ad313 | ChEMBL |
| Manual Xrefs | Databases |
|---|---|
| 256 | DrugCentral |
| Atomoxetine | Wikipedia |
| D07473 | KEGG DRUG |
| DB00289 | DrugBank |
| HMDB0014434 | HMDB |
| LSM-2452 | LINCS |
| Registry Numbers | Sources |
|---|---|
| Reaxys:4318684 | Reaxys |
| CAS:83015-26-3 | KEGG DRUG |
| CAS:83015-26-3 | ChemIDplus |
| Citations |
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