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CHEBI:32292 - vedaprofen
| ChEBI ID | CHEBI:32292 |
| ChEBI Name | vedaprofen |
| Stars | |
| Definition | A racemate composed of equal amounts of (R)- and (S)-vedaprofen. Used for control of pain and inflammation particularly associated with chronic musculoskeletal disorders and soft tissue trauma in dogs and horses and for treatment of pain due to horse colic. |
| Last Modified | 19 September 2018 |
| Formula | C19H22O2 |
| Net Charge | 0 |
| Average Mass | 282.377 |
| Monoisotopic Mass | 282.16198 |
| Wikipedia |
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| Roles Classification |
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| Biological Roles: | EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor A compound or agent that combines with cyclooxygenases (EC 1.14.99.1) and thereby prevents its substrate-enzyme combination with arachidonic acid and the formation of icosanoids, prostaglandins, and thromboxanes. non-narcotic analgesic A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors. |
| Applications: | anti-ulcer drug One of various classes of drugs with different action mechanisms used to treat or ameliorate peptic ulcer or irritation of the gastrointestinal tract. non-narcotic analgesic A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors. non-steroidal anti-inflammatory drug An anti-inflammatory drug that is not a steroid. In addition to anti-inflammatory actions, non-steroidal anti-inflammatory drugs have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. |
| ChEBI Ontology |
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| Outgoing Relation(s) |
| vedaprofen (CHEBI:32292) has part (R)-vedaprofen (CHEBI:76285) |
| vedaprofen (CHEBI:32292) has part (S)-vedaprofen (CHEBI:76286) |
| vedaprofen (CHEBI:32292) has role anti-ulcer drug (CHEBI:49201) |
| vedaprofen (CHEBI:32292) has role EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor (CHEBI:35544) |
| vedaprofen (CHEBI:32292) has role non-narcotic analgesic (CHEBI:35481) |
| vedaprofen (CHEBI:32292) has role non-steroidal anti-inflammatory drug (CHEBI:35475) |
| vedaprofen (CHEBI:32292) is a racemate (CHEBI:60911) |
| IUPAC Name |
|---|
| rac-2-(4-cyclohexyl-1-naphthyl)propanoic acid |
| INNs | Source |
|---|---|
| vedaprofen | KEGG DRUG |
| vedaprofeno | WHO MedNet |
| védaprofène | WHO MedNet |
| vedaprofenum | WHO MedNet |
| Synonyms | Source |
|---|---|
| (±)-4-cyclohexyl-α-methyl-1-naphthaleneacetic acid | ChemIDplus |
| racemic vedaprofen | ChEBI |
| DL-vedaprofen | ChEBI |
| (RS)-vedaprofen | ChEBI |
| (±)-vedaprofen | ChEBI |
| Manual Xrefs | Databases |
|---|---|
| D01874 | KEGG DRUG |
| US4218473 | Patent |
| Vedaprofen | Wikipedia |
| 2812 | DrugCentral |
| 1908 | VSDB |
| Registry Numbers | Sources |
|---|---|
| Reaxys:5568831 | Reaxys |
| CAS:71109-09-6 | KEGG DRUG |
| CAS:71109-09-6 | ChemIDplus |
| Citations |
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