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CHEBI:32270 - trospium chloride

Default Structure
ChEBI IDCHEBI:32270
ChEBI Nametrospium chloride
Stars
DefinitionAn organic chloride salt of trospium. It is an antispasmodic drug used for the treatment of overactive bladder.
Last Modified17 January 2020
DownloadsMolfile
FormulaC25H30NO3.Cl
Net Charge0
Average Mass427.972
Monoisotopic Mass427.19142
SMILES[Cl-].[H][C@]12CC[C@]([H])(C[C@H](OC(=O)C(O)(c3ccccc3)c3ccccc3)C1)[N+]21CCCC1
InChIInChI=1S/C25H30NO3.ClH/c27-24(25(28,19-9-3-1-4-10-19)20-11-5-2-6-12-20)29-23-17-21-13-14-22(18-23)26(21)15-7-8-16-26;/h1-6,9-12,21-23,28H,7-8,13-18H2;1H/q+1;/p-1/t21-,22+,23+;
InChIKeyRVCSYOQWLPPAOA-QKYUOBHYSA-M
Wikipedia
Roles Classification
Biological Role:
muscarinic antagonist  A drug that binds to but does not activate muscarinic cholinergic receptors, thereby blocking the actions of endogenous acetylcholine or exogenous agonists.
Applications:
muscarinic antagonist  A drug that binds to but does not activate muscarinic cholinergic receptors, thereby blocking the actions of endogenous acetylcholine or exogenous agonists.
antipsychotic agent  Antipsychotic drugs are agents that control agitated psychotic behaviour, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect.
antispasmodic drug  A drug that suppresses spasms. These are usually caused by smooth muscle contraction, especially in tubular organs. The effect is to prevent spasms of the stomach, intestine or urinary bladder.
ChEBI Ontology
Outgoing Relation(s)
trospium chloride (CHEBI:32270) has part trospium (CHEBI:145791)
trospium chloride (CHEBI:32270) has role antipsychotic agent (CHEBI:35476)
trospium chloride (CHEBI:32270) has role antispasmodic drug (CHEBI:53784)
trospium chloride (CHEBI:32270) has role muscarinic antagonist (CHEBI:48876)
trospium chloride (CHEBI:32270) is a organic chloride salt (CHEBI:36094)
trospium chloride (CHEBI:32270) is a quaternary ammonium salt (CHEBI:35273)
IUPAC Name 
(1S,3R,5R)-3-[(2-hydroxy-2,2-diphenylacetyl)oxy]-8λ5-azaspiro[bicyclo[3.2.1]octane-8,1'-pyrrolidin]-8-ylium chloride
INNs  Source
chlorure de trospiumWHO MedNet
cloruro de trospioWHO MedNet
trospii chloridumWHO MedNet
trospium chlorideWHO MedNet
Synonyms  Source
IP-631ChEBI
IP631ChemIDplus
Trospium chlorideKEGG DRUG
trospium ClChemIDplus
Brand Names  Source
FlotrosChEMBL
RegurinChEBI
Regurin xlChEMBL
RelaspiumChemIDplus
SancturaChemIDplus
Sanctura XRChemIDplus
Manual XrefsDatabases
2776DrugCentral
D01103KEGG DRUG
DBSALT000883DrugBank
Trospium_chlorideWikipedia
Registry NumbersSources
CAS:10405-02-4ChemIDplus
Citations