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CHEBI:32265 - triprolidine hydrochloride monohydrate

ChEBI IDCHEBI:32265
ChEBI Nametriprolidine hydrochloride monohydrate
Stars
DefinitionA hydrate that is the monohydrate form of triprolidine hydrochloride. A sedating antihistamine, it is used for the symptomatic relief of uticaria, rhinitis, and various pruritic skin disorders.
Last Modified17 December 2014
DownloadsMolfile
FormulaC19H22N2.H2O.HCl
Net Charge0
Average Mass332.875
Monoisotopic Mass332.16554
SMILESCl.O.[H]/C(CN1CCCC1)=C(/c1ccc(C)cc1)c1ccccn1
InChIInChI=1S/C19H22N2.ClH.H2O/c1-16-7-9-17(10-8-16)18(19-6-2-3-12-20-19)11-15-21-13-4-5-14-21;;/h2-3,6-12H,4-5,13-15H2,1H3;1H;1H2/b18-11+;;
InChIKeyCUZMOIXUFHOLLN-UMVVUDSKSA-N
Roles Classification
Biological Role:
H1-receptor antagonist  H1-receptor antagonists are the drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine.
Application:
H1-receptor antagonist  H1-receptor antagonists are the drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine.
ChEBI Ontology
Outgoing Relation(s)
triprolidine hydrochloride monohydrate (CHEBI:32265) has part triprolidine hydrochloride (anh.) (CHEBI:84119)
triprolidine hydrochloride monohydrate (CHEBI:32265) has role H1-receptor antagonist (CHEBI:37955)
triprolidine hydrochloride monohydrate (CHEBI:32265) is a hydrate (CHEBI:35505)
IUPAC Name 
2-[(1E)-1-(4-methylphenyl)-3-(pyrrolidin-1-yl)prop-1-en-1-yl]pyridine hydrochloride—water (1/1)
Synonym  Source
1-[(2E)-3-(4-methylphenyl)-3-(pyridin-2-yl)prop-2-en-1-yl]pyrrolidinium chloride—water (1/1)IUPAC
Brand Names  Source
Pro-ActidilChEBI
VenenKEGG DRUG
ActidilonChEBI
Pro-EntraChEBI
ActidilChEBI
Manual XrefsDatabases
D01782KEGG DRUG
DB00427DrugBank
Registry NumbersSources
CAS:6138-79-0ChemIDplus
Citations