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CHEBI:32232 - tiquizium bromide

ChEBI IDCHEBI:32232
ChEBI Nametiquizium bromide
Stars
DefinitionA organic bromide salt of tiquizium. It is an antispasmodic drug used for the treatment of convulsion and hypermobility in gastritis, gastric ulcer, duodenal ulcer, enteritis, irritable bowel syndrome, gallbladder disease, biliary tract disease and urolithiasis.
Last Modified20 December 2019
DownloadsMolfile
FormulaBr.C19H24NS2
Net Charge0
Average Mass410.446
Monoisotopic Mass409.05335
SMILES[Br-].[H][C@]12CCCC[N@+]1(C)CC(=C(c1cccs1)c1cccs1)CC2
InChIInChI=1S/C19H24NS2.BrH/c1-20-11-3-2-6-16(20)10-9-15(14-20)19(17-7-4-12-21-17)18-8-5-13-22-18;/h4-5,7-8,12-13,16H,2-3,6,9-11,14H2,1H3;1H/q+1;/p-1/t16-,20-;/m1./s1
InChIKeyVKBNGRDAHSELMQ-KYSFMIDTSA-M
Roles Classification
Biological Role:
muscarinic antagonist  A drug that binds to but does not activate muscarinic cholinergic receptors, thereby blocking the actions of endogenous acetylcholine or exogenous agonists.
Applications:
antispasmodic drug  A drug that suppresses spasms. These are usually caused by smooth muscle contraction, especially in tubular organs. The effect is to prevent spasms of the stomach, intestine or urinary bladder.
anti-ulcer drug  One of various classes of drugs with different action mechanisms used to treat or ameliorate peptic ulcer or irritation of the gastrointestinal tract.
muscarinic antagonist  A drug that binds to but does not activate muscarinic cholinergic receptors, thereby blocking the actions of endogenous acetylcholine or exogenous agonists.
ChEBI Ontology
Outgoing Relation(s)
tiquizium bromide (CHEBI:32232) has part tiquizium (CHEBI:145714)
tiquizium bromide (CHEBI:32232) has role anti-ulcer drug (CHEBI:49201)
tiquizium bromide (CHEBI:32232) has role antispasmodic drug (CHEBI:53784)
tiquizium bromide (CHEBI:32232) has role muscarinic antagonist (CHEBI:48876)
tiquizium bromide (CHEBI:32232) is a organic bromide salt (CHEBI:48369)
tiquizium bromide (CHEBI:32232) is a quaternary ammonium salt (CHEBI:35273)
IUPAC Name 
(5R,9aR)-3-[di(thiophen-2-yl)methylidene]-5-methyloctahydro-2H-quinolizinium bromide
INNs  Source
tiquizium bromideWHO MedNet
bromuro de tiquizioWHO MedNet
bromure de tiquiziumWHO MedNet
tiquizii bromidumWHO MedNet
Synonyms  Source
HSR 902ChEBI
HSR-902ChemIDplus
(5R,9aR)-3-[di(thiophen-2-yl)methylidene]-5-methyloctahydro-2H-quinolizin-5-ium bromideIUPAC
3-(di(2-thienyl)methylene)-5-methyldecahydroquinolizinium bromideChemIDplus
trans-3-(di-2-thienylmethylene)octahydro-5-methyl-2H-quinolizinium bromideChemIDplus
3-(di-2-thienylmethylene)-5-methyl-trans-quinolizidinium bromideChEBI
Brand Names  Source
ThiatonKEGG DRUG
TiapastonChEBI
ThiameronChEBI
GastirolChEBI
AdvastonChEBI
ThiwanChEBI
Manual XrefsDatabases
D01875KEGG DRUG
2678DrugCentral
Registry NumbersSources
CAS:71731-58-3ChemIDplus
Citations