EMBL-EBI | Chemical Biology | ChEBI

Example searches: iron*, InChI=1S/CH4O/c1-2/h2H,1H3, caffeine | Advanced Search

CHEBI:145714 - tiquizium

ChEBI IDCHEBI:145714
ChEBI Nametiquizium
Stars
DefinitionA member of the class of quinolizines that is trans-5-methyloctahydro-2H-quinolizinium which is substituted by a di(thiophen-2-yl)methylidene group at position 3. Its bromide salt is used as an antispasmodic drug.
Last Modified20 December 2019
SubmitterAdnan
DownloadsMolfile
FormulaC19H24NS2
Net Charge+1
Average Mass330.542
Monoisotopic Mass330.13447
SMILES[H][C@]12CCCC[N@+]1(C)CC(=C(c1cccs1)c1cccs1)CC2
InChIInChI=1S/C19H24NS2/c1-20-11-3-2-6-16(20)10-9-15(14-20)19(17-7-4-12-21-17)18-8-5-13-22-18/h4-5,7-8,12-13,16H,2-3,6,9-11,14H2,1H3/q+1/t16-,20-/m1/s1
InChIKeyZGSDGGRVFIYKKE-OXQOHEQNSA-N
Roles Classification
Biological Role:
muscarinic antagonist  A drug that binds to but does not activate muscarinic cholinergic receptors, thereby blocking the actions of endogenous acetylcholine or exogenous agonists.
Applications:
muscarinic antagonist  A drug that binds to but does not activate muscarinic cholinergic receptors, thereby blocking the actions of endogenous acetylcholine or exogenous agonists.
antispasmodic drug  A drug that suppresses spasms. These are usually caused by smooth muscle contraction, especially in tubular organs. The effect is to prevent spasms of the stomach, intestine or urinary bladder.
anti-ulcer drug  One of various classes of drugs with different action mechanisms used to treat or ameliorate peptic ulcer or irritation of the gastrointestinal tract.
ChEBI Ontology
Outgoing Relation(s)
tiquizium (CHEBI:145714) has role anti-ulcer drug (CHEBI:49201)
tiquizium (CHEBI:145714) has role antispasmodic drug (CHEBI:53784)
tiquizium (CHEBI:145714) has role muscarinic antagonist (CHEBI:48876)
tiquizium (CHEBI:145714) is a quaternary ammonium ion (CHEBI:35267)
tiquizium (CHEBI:145714) is a quinolizines (CHEBI:38063)
tiquizium (CHEBI:145714) is a thiophenes (CHEBI:26961)
Incoming Relation(s)
tiquizium bromide (CHEBI:32232) has part tiquizium (CHEBI:145714)
IUPAC Name 
(5R,9aR)-3-[di(thiophen-2-yl)methylidene]-5-methyloctahydro-2H-quinolizinium
Synonyms  Source
(5R,9aR)-3-[di(thiophen-2-yl)methylidene]-5-methyloctahydro-2H-quinolizin-5-iumIUPAC
trans-3-(di-2-thienylmethylene)octahydro-5-methyl-2H-quinoliziniumChemIDplus
3-(di-2-thienylmethylene)-octahydro-5-methyl-trans-quinoliziniumChEBI
Manual XrefsDatabases
2678DrugCentral
Registry NumbersSources
CAS:149755-23-7ChemIDplus
Citations