EMBL-EBI | Chemical Biology | ChEBI

Example searches: iron*, InChI=1S/CH4O/c1-2/h2H,1H3, caffeine | Advanced Search

CHEBI:32184 - tazarotene

ChEBI IDCHEBI:32184
ChEBI Nametazarotene
Stars
DefinitionThe ethyl ester of tazarotenic acid. A prodrug for tazarotenic acid, it is used for the treatment of psoriasis, acne, and sun-damaged skin.
Last Modified22 February 2017
DownloadsMolfile
FormulaC21H21NO2S
Net Charge0
Average Mass351.471
Monoisotopic Mass351.12930
SMILESCCOC(=O)c1ccc(C#Cc2ccc3c(c2)C(C)(C)CCS3)nc1
InChIInChI=1S/C21H21NO2S/c1-4-24-20(23)16-7-9-17(22-14-16)8-5-15-6-10-19-18(13-15)21(2,3)11-12-25-19/h6-7,9-10,13-14H,4,11-12H2,1-3H3
InChIKeyOGQICQVSFDPSEI-UHFFFAOYSA-N
Wikipedia
Roles Classification
Biological Role:
teratogenic agent  A role played by a chemical compound in biological systems with adverse consequences in embryo developments, leading to birth defects, embryo death or altered development, growth retardation and functional defect.
Applications:
prodrug  A compound that, on administration, must undergo chemical conversion by metabolic processes before becoming the pharmacologically active drug for which it is a prodrug.
keratolytic drug  A drug that softens, separates, and causes desquamation of the cornified epithelium or horny layer of skin. Keratolytic drugs are used to expose mycelia of infecting fungi or to treat corns, warts, and certain other skin diseases.
ChEBI Ontology
Outgoing Relation(s)
tazarotene (CHEBI:32184) has functional parent tazarotenic acid (CHEBI:73129)
tazarotene (CHEBI:32184) has role keratolytic drug (CHEBI:50176)
tazarotene (CHEBI:32184) has role prodrug (CHEBI:50266)
tazarotene (CHEBI:32184) has role teratogenic agent (CHEBI:50905)
tazarotene (CHEBI:32184) is a acetylenic compound (CHEBI:73474)
tazarotene (CHEBI:32184) is a ethyl ester (CHEBI:23990)
tazarotene (CHEBI:32184) is a pyridines (CHEBI:26421)
tazarotene (CHEBI:32184) is a retinoid (CHEBI:26537)
tazarotene (CHEBI:32184) is a thiochromane (CHEBI:50747)
IUPAC Name 
ethyl 6-[(4,4-dimethyl-3,4-dihydro-2H-thiochromen-6-yl)ethynyl]nicotinate
INNs  Source
tazaroteneChemIDplus
tazarotèneChEBI
tazarotenoChEBI
tazarotenumChEBI
Brand Names  Source
TazoracDrugBank
ZoracDrugBank
AvageChemIDplus
Manual XrefsDatabases
C12531KEGG COMPOUND
D01132KEGG DRUG
DB00799DrugBank
EP284288Patent
US5089509Patent
TazaroteneWikipedia
HMDB0014937HMDB
2571DrugCentral
Registry NumbersSources
Beilstein:8159145Beilstein
CAS:118292-40-3ChemIDplus