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CHEBI:31859 - modafinil
| ChEBI ID | CHEBI:31859 |
| ChEBI Name | modafinil |
| Stars | |
| Definition | A racemate comprising equimolar amounts of armodafinil and (S)-modafinil. A central nervous system stimulant, it is used for the treatment of sleeping disorders such as narcolepsy, obstructive sleep apnoea, and shift-work sleep disorder. The optical enantiomers of modafinil have similar pharmacological actions in animals. |
| Last Modified | 22 February 2017 |
| Wikipedia |
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| Roles Classification |
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| Biological Roles: | analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. immunosuppressive agent An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response. |
| Applications: | antidepressant Antidepressants are mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. central nervous system stimulant Any drug that enhances the activity of the central nervous system. eugeroic A phsychotropic drug that improves wakefulness and alertness, and reduces tiredness, drowsiness, and the need for sleep. Eugeroics are relatively non-addictive and are used in the treatment of narcolepsy and other sleep disorders. analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. antipsychotic agent Antipsychotic drugs are agents that control agitated psychotic behaviour, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect. immunosuppressive agent An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response. vasoconstrictor agent Drug used to cause constriction of the blood vessels. antiparkinson drug A drug used in the treatment of Parkinson's disease. |
| ChEBI Ontology |
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| Outgoing Relation(s) |
| modafinil (CHEBI:31859) has part (S)-modafinil (CHEBI:77591) |
| modafinil (CHEBI:31859) has part armodafinil (CHEBI:77590) |
| modafinil (CHEBI:31859) has role analgesic (CHEBI:35480) |
| modafinil (CHEBI:31859) has role antidepressant (CHEBI:35469) |
| modafinil (CHEBI:31859) has role antineoplastic agent (CHEBI:35610) |
| modafinil (CHEBI:31859) has role antiparkinson drug (CHEBI:48407) |
| modafinil (CHEBI:31859) has role antipsychotic agent (CHEBI:35476) |
| modafinil (CHEBI:31859) has role central nervous system stimulant (CHEBI:35337) |
| modafinil (CHEBI:31859) has role eugeroic (CHEBI:77567) |
| modafinil (CHEBI:31859) has role immunosuppressive agent (CHEBI:35705) |
| modafinil (CHEBI:31859) has role vasoconstrictor agent (CHEBI:50514) |
| modafinil (CHEBI:31859) is a organic molecular entity (CHEBI:50860) |
| modafinil (CHEBI:31859) is a racemate (CHEBI:60911) |
| IUPAC Name |
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| rac-2-[(diphenylmethyl)sulfinyl]acetamide |
| INNs | Source |
|---|---|
| modafinil | WHO MedNet |
| modafinil | WHO MedNet |
| modafinilo | WHO MedNet |
| modafinilum | WHO MedNet |
| Synonyms | Source |
|---|---|
| 2-(benzhydrylsulfinyl)acetamide | ChemIDplus |
| CEP 1538 | ChEMBL |
| CEP-1538 | ChEBI |
| CRC-40476 | ChEMBL |
| CRL 40476 | ChemIDplus |
| CRL-40476 | ChEBI |
| Brand Name | Source |
|---|---|
| Provigil | KEGG DRUG |
| Registry Numbers | Sources |
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| Reaxys:1978970 | Reaxys |
| CAS:68693-11-8 | ChemIDplus |
| Citations |
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