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CHEBI:31749 - kebuzone

ChEBI IDCHEBI:31749
ChEBI Namekebuzone
Stars
DefinitionA pyrazolidine that is phenylbutazone in which the two methylene hydrogens at postion 3 on the butyl chain are replaced by an oxo group.
Last Modified22 February 2017
DownloadsMolfile
FormulaC19H18N2O3
Net Charge0
Average Mass322.364
Monoisotopic Mass322.13174
SMILESCC(=O)CCC1C(=O)N(c2ccccc2)N(c2ccccc2)C1=O
InChIInChI=1S/C19H18N2O3/c1-14(22)12-13-17-18(23)20(15-8-4-2-5-9-15)21(19(17)24)16-10-6-3-7-11-16/h2-11,17H,12-13H2,1H3
InChIKeyLGYTZKPVOAIUKX-UHFFFAOYSA-N
Wikipedia
Roles Classification
Biological Role:
non-narcotic analgesic  A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors.
Applications:
non-narcotic analgesic  A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors.
non-steroidal anti-inflammatory drug  An anti-inflammatory drug that is not a steroid. In addition to anti-inflammatory actions, non-steroidal anti-inflammatory drugs have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins.
ChEBI Ontology
Outgoing Relation(s)
kebuzone (CHEBI:31749) has functional parent phenylbutazone (CHEBI:48574)
kebuzone (CHEBI:31749) has role non-narcotic analgesic (CHEBI:35481)
kebuzone (CHEBI:31749) has role non-steroidal anti-inflammatory drug (CHEBI:35475)
kebuzone (CHEBI:31749) is a methyl ketone (CHEBI:51867)
kebuzone (CHEBI:31749) is a pyrazolidines (CHEBI:38312)
INNs  Source
kebuzoneKEGG DRUG
quebuzonaChemIDplus
kebuzonumChemIDplus
kébuzoneWHO MedNet
Synonyms  Source
KetophenylbutazoneKEGG DRUG
1,2-Diphenyl-4-(gamma-ketobutyl)-3,5-pyrazolidinedioneChemIDplus
4-(3-Oxobutyl)-1,2-diphenyl-3,5-pyrazolidinedioneChemIDplus
KetophenylbutazonumChemIDplus
Manual XrefsDatabases
D01567KEGG DRUG
WO2007128412Patent
HMDB0041914HMDB
KebuzoneWikipedia
1522DrugCentral
Registry NumbersSources
Reaxys:308507Reaxys
CAS:853-34-9KEGG DRUG
CAS:853-34-9ChemIDplus
Citations