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CHEBI:31633 - formoterol fumarate
| ChEBI ID | CHEBI:31633 |
| ChEBI Name | formoterol fumarate |
| Stars | |
| Definition | A racemate consisting of equal amounts of arformoterol fumarate (the active enantiomer) and (S,S)-formoterol fumarate (the inactive enantiomer). It is used (particularly in its dihydrate form) as a direct-acting sympathomimetic and bronchodilator for the treatment of chronic obstructive pulmonary disease (any progressive respiratory disease that makes it harder to breathe over time, such as chronic bronchitis and emphysema). |
| Last Modified | 9 September 2016 |
| Formula | C42H52N4O12 |
| Net Charge | 0 |
| Average Mass | 804.882 |
| Monoisotopic Mass | 804.35817 |
| Roles Classification |
|---|
| Biological Role: | beta-adrenergic agonist An agent that selectively binds to and activates β-adrenergic receptors. |
| Applications: | antispasmodic drug A drug that suppresses spasms. These are usually caused by smooth muscle contraction, especially in tubular organs. The effect is to prevent spasms of the stomach, intestine or urinary bladder. bronchodilator agent An agent that causes an increase in the expansion of a bronchus or bronchial tubes. antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. anti-asthmatic agent Any compound that has anti-asthmatic effects. beta-adrenergic agonist An agent that selectively binds to and activates β-adrenergic receptors. anti-asthmatic drug A drug used to treat asthma. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| formoterol fumarate (CHEBI:31633) has part (S,S)-formoterol fumarate (CHEBI:63109) |
| formoterol fumarate (CHEBI:31633) has part arformoterol fumarate (CHEBI:63108) |
| formoterol fumarate (CHEBI:31633) has part formoterol(1+) (CHEBI:63111) |
| formoterol fumarate (CHEBI:31633) has role anti-asthmatic agent (CHEBI:65023) |
| formoterol fumarate (CHEBI:31633) has role anti-asthmatic drug (CHEBI:49167) |
| formoterol fumarate (CHEBI:31633) has role antineoplastic agent (CHEBI:35610) |
| formoterol fumarate (CHEBI:31633) has role antispasmodic drug (CHEBI:53784) |
| formoterol fumarate (CHEBI:31633) has role bronchodilator agent (CHEBI:35523) |
| formoterol fumarate (CHEBI:31633) has role β-adrenergic agonist (CHEBI:35522) |
| formoterol fumarate (CHEBI:31633) is a racemate (CHEBI:60911) |
| Incoming Relation(s) |
| Bevespi Aerosphere (CHEBI:133025) has part formoterol fumarate (CHEBI:31633) |
| IUPAC Name |
|---|
| rac-bis[(2R)-N-{(2R)-2-[3-(formylamino)-4-hydroxyphenyl]-2-hydroxyethyl}-1-(4-methoxyphenyl)propan-2-aminium] (2E)-but-2-enedioate |
| Synonyms | Source |
|---|---|
| Atock | ChEMBL |
| BD 40A | ChEMBL |
| BD-40A | ChEMBL |
| CGP 25827A | ChEMBL |
| rac-N-{2-hydroxy-5-[(1R)-1-hydroxy-2-{[(2R)-1-(4-methoxyphenyl)propan-2-yl]amino}ethyl]phenyl}formamide (2E)-but-2-enedioate | IUPAC |
| Fomoterol fumarate | ChEMBL |
| Brand Names | Source |
|---|---|
| Atimos modulite | ChEMBL |
| Foradil | ChEMBL |
| Foradil certihaler | ChEMBL |
| Formoterol fumarate component of bevespi aerosphere | ChEMBL |
| Formoterol fumarate component of breztri | ChEMBL |
| Formoterol fumarate component of duaklir pressair | ChEMBL |
| Registry Numbers | Sources |
|---|---|
| Reaxys:8463050 | Reaxys |
| CAS:43229-80-7 | ChemIDplus |
| CAS:43229-80-7 | KEGG DRUG |
| Citations |
|---|