EMBL-EBI | Chemical Biology | ChEBI
Example searches: iron*, InChI=1S/CH4O/c1-2/h2H,1H3, caffeine | Advanced Search
CHEBI:31633 - formoterol fumarate
| ChEBI ID | CHEBI:31633 |
| ChEBI Name | formoterol fumarate |
| Stars | |
| Definition | A racemate consisting of equal amounts of arformoterol fumarate (the active enantiomer) and (S,S)-formoterol fumarate (the inactive enantiomer). It is used (particularly in its dihydrate form) as a direct-acting sympathomimetic and bronchodilator for the treatment of chronic obstructive pulmonary disease (any progressive respiratory disease that makes it harder to breathe over time, such as chronic bronchitis and emphysema). |
| Last Modified | 9 September 2016 |
| Formula | C42H52N4O12 |
| Net Charge | 0 |
| Average Mass | 804.882 |
| Monoisotopic Mass | 804.35817 |
| Roles Classification |
|---|
| Biological Role: | beta-adrenergic agonist An agent that selectively binds to and activates β-adrenergic receptors. |
| Applications: | beta-adrenergic agonist An agent that selectively binds to and activates β-adrenergic receptors. anti-asthmatic drug A drug used to treat asthma. bronchodilator agent An agent that causes an increase in the expansion of a bronchus or bronchial tubes. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| formoterol fumarate (CHEBI:31633) has part (S,S)-formoterol fumarate (CHEBI:63109) |
| formoterol fumarate (CHEBI:31633) has part arformoterol fumarate (CHEBI:63108) |
| formoterol fumarate (CHEBI:31633) has part formoterol(1+) (CHEBI:63111) |
| formoterol fumarate (CHEBI:31633) has role anti-asthmatic drug (CHEBI:49167) |
| formoterol fumarate (CHEBI:31633) has role bronchodilator agent (CHEBI:35523) |
| formoterol fumarate (CHEBI:31633) has role β-adrenergic agonist (CHEBI:35522) |
| formoterol fumarate (CHEBI:31633) is a racemate (CHEBI:60911) |
| Incoming Relation(s) |
| Bevespi Aerosphere (CHEBI:133025) has part formoterol fumarate (CHEBI:31633) |
| IUPAC Name |
|---|
| rac-bis[(2R)-N-{(2R)-2-[3-(formylamino)-4-hydroxyphenyl]-2-hydroxyethyl}-1-(4-methoxyphenyl)propan-2-aminium] (2E)-but-2-enedioate |
| Synonyms | Source |
|---|---|
| formoterol hemifumarate | ChEBI |
| rac-N-{2-hydroxy-5-[(1R)-1-hydroxy-2-{[(2R)-1-(4-methoxyphenyl)propan-2-yl]amino}ethyl]phenyl}formamide (2E)-but-2-enedioate | IUPAC |
| Registry Numbers | Sources |
|---|---|
| Reaxys:8463050 | Reaxys |
| CAS:43229-80-7 | KEGG DRUG |
| CAS:43229-80-7 | ChemIDplus |
| Citations |
|---|