CHEBI:31568 - profenamine hydrochloride

ChEBI IDCHEBI:31568
ChEBI Nameprofenamine hydrochloride
Stars
DefinitionThe monohydrochloride salt of profenamine. An antimuscarinic, it is used for the symptomatic treatment of Parkinson's disease.
Last Modified14 June 2018
DownloadsMolfile
FormulaC19H24N2S.HCl
Net Charge0
Average Mass348.943
Monoisotopic Mass348.14270
SMILESCCN(CC)C(C)CN1c2ccccc2Sc2ccccc21.Cl
InChIInChI=1S/C19H24N2S.ClH/c1-4-20(5-2)15(3)14-21-16-10-6-8-12-18(16)22-19-13-9-7-11-17(19)21;/h6-13,15H,4-5,14H2,1-3H3;1H
InChIKeyVXPCQISYVPFYRK-UHFFFAOYSA-N
Roles Classification
Biological Roles:
histamine antagonist  Histamine antagonists are the drugs that bind to but do not activate histamine receptors, thereby blocking the actions of histamine or histamine agonists.
adrenergic antagonist  An agent that binds to but does not activate adrenergic receptors thereby blocking the actions of endogenous or exogenous adrenergic agonists.
muscarinic antagonist  A drug that binds to but does not activate muscarinic cholinergic receptors, thereby blocking the actions of endogenous acetylcholine or exogenous agonists.
Applications:
antiparkinson drug  A drug used in the treatment of Parkinson's disease.
histamine antagonist  Histamine antagonists are the drugs that bind to but do not activate histamine receptors, thereby blocking the actions of histamine or histamine agonists.
adrenergic antagonist  An agent that binds to but does not activate adrenergic receptors thereby blocking the actions of endogenous or exogenous adrenergic agonists.
muscarinic antagonist  A drug that binds to but does not activate muscarinic cholinergic receptors, thereby blocking the actions of endogenous acetylcholine or exogenous agonists.
ChEBI Ontology
Outgoing Relation(s)
profenamine hydrochloride (CHEBI:31568) has part profenamine (CHEBI:313639)
profenamine hydrochloride (CHEBI:31568) has role adrenergic antagonist (CHEBI:37887)
profenamine hydrochloride (CHEBI:31568) has role antiparkinson drug (CHEBI:48407)
profenamine hydrochloride (CHEBI:31568) has role histamine antagonist (CHEBI:37956)
profenamine hydrochloride (CHEBI:31568) has role muscarinic antagonist (CHEBI:48876)
profenamine hydrochloride (CHEBI:31568) is a hydrochloride (CHEBI:36807)
IUPAC Name 
N,N-diethyl-1-(10H-phenothiazin-10-yl)propan-2-amine hydrochloride
Synonyms  Source
ethopropazine HClChemIDplus
ethopropazine monohydrochlorideChEBI
10-(2-(diethylamino)propyl)phenothiazine monohydrochlorideChemIDplus
ethopropazine hydrochlorideChemIDplus
N,N-diethyl-α-methyl-10H-phenothiazine-10-ethylamine hydrochlorideChEBI
profenamine monohydrochlorideChemIDplus
Manual XrefsDatabases
D01118KEGG DRUG
DB00392DrugBank
Registry NumbersSources
CAS:1094-08-2KEGG DRUG
CAS:1094-08-2ChemIDplus
Citations