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CHEBI:31556 - esatenolol

Default Structure
ChEBI IDCHEBI:31556
ChEBI Nameesatenolol
Stars
DefinitionThe (S)-enantiomer of atenolol.
Last Modified22 February 2017
DownloadsMolfile
FormulaC14H22N2O3
Net Charge0
Average Mass266.341
Monoisotopic Mass266.16304
SMILESCC(C)NC[C@H](O)COc1ccc(CC(N)=O)cc1
InChIInChI=1S/C14H22N2O3/c1-10(2)16-8-12(17)9-19-13-5-3-11(4-6-13)7-14(15)18/h3-6,10,12,16-17H,7-9H2,1-2H3,(H2,15,18)/t12-/m0/s1
InChIKeyMETKIMKYRPQLGS-LBPRGKRZSA-N
Roles Classification
Chemical Roles:
environmental contaminant  Any minor or unwanted substance introduced into the environment that can have undesired effects.
Bronsted base  A molecular entity capable of accepting a hydron from a donor (Brønsted acid).
Bronsted base  A molecular entity capable of accepting a hydron from a donor (Brønsted acid).
Biological Roles:
beta-adrenergic antagonist  An agent that binds to but does not activate β-adrenergic receptors thereby blocking the actions of endogenous or exogenous β-adrenergic agonists. β-Adrenergic antagonists are used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches and anxiety.
beta-adrenergic antagonist  An agent that binds to but does not activate β-adrenergic receptors thereby blocking the actions of endogenous or exogenous β-adrenergic agonists. β-Adrenergic antagonists are used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches and anxiety.
xenobiotic  A xenobiotic (Greek, xenos "foreign"; bios "life") is a compound that is foreign to a living organism. Principal xenobiotics include: drugs, carcinogens and various compounds that have been introduced into the environment by artificial means.
sympatholytic agent  Any compound which inhibits the postganglionic functioning of the sympathetic nervous system (SNS).
Applications:
cardiovascular drug  A drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume.
beta-adrenergic antagonist  An agent that binds to but does not activate β-adrenergic receptors thereby blocking the actions of endogenous or exogenous β-adrenergic agonists. β-Adrenergic antagonists are used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches and anxiety.
anti-arrhythmia drug  A drug used for the treatment or prevention of cardiac arrhythmias. Anti-arrhythmia drugs may affect the polarisation-repolarisation phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibres.
hypoglycemic agent  A drug which lowers the blood glucose level.
beta-adrenergic antagonist  An agent that binds to but does not activate β-adrenergic receptors thereby blocking the actions of endogenous or exogenous β-adrenergic agonists. β-Adrenergic antagonists are used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches and anxiety.
antineoplastic agent  A substance that inhibits or prevents the proliferation of neoplasms.
antihypertensive agent  Any drug used in the treatment of acute or chronic vascular hypertension regardless of pharmacological mechanism.
bone density conservation agent  An agent that inhibits bone resorption and/or favor bone mineralization and bone regeneration. Used to heal bone fractures and to treat bone diseases such as osteopenia and osteoporosis.
cardiovascular drug  A drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume.
antidepressant  Antidepressants are mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions.
sympatholytic agent  Any compound which inhibits the postganglionic functioning of the sympathetic nervous system (SNS).
ChEBI Ontology
Outgoing Relation(s)
esatenolol (CHEBI:31556) has role cardiovascular drug (CHEBI:35554)
esatenolol (CHEBI:31556) has role β-adrenergic antagonist (CHEBI:35530)
esatenolol (CHEBI:31556) is a atenolol (CHEBI:2904)
IUPAC Name 
2-[4-({(2S)2-hydroxy-3-[(propan-2-yl)amino]propyl}oxy)phenyl]acetamide
INN  Source
esatenololKEGG DRUG
Synonyms  Source
2-(p-((2S)-2-Hydroxy-3-(isopropylamino)propoxy)phenyl)acetamideChemIDplus
(-)-AtenololChemIDplus
Atenolol, (-)-ChEMBL
Atenolol, (s)-ChEMBL
(S)-4-(2-Hydroxy-3-((1-methylethyl)amino)propoxy)benzeneacetamideChemIDplus
S-(-)-4-(2-Hydroxy-3-isopropylaminopropoxy)phenylacetamideChemIDplus
Manual XrefsDatabases
4702DrugCentral
D01471KEGG DRUG
DB00335DrugBank
LSM-5562LINCS
Registry NumbersSources
Beilstein:4234251Beilstein
CAS:93379-54-5ChemIDplus
CAS:93379-54-5KEGG DRUG
Citations