EMBL-EBI | Chemical Biology | ChEBI
Example searches: iron*, InChI=1S/CH4O/c1-2/h2H,1H3, caffeine | Advanced Search
CHEBI:2904 - atenolol
| Formula | C14H22N2O3 |
| Net Charge | 0 |
| Average Mass | 266.341 |
| Monoisotopic Mass | 266.16304 |
| SMILES | CC(C)NCC(O)COc1ccc(CC(N)=O)cc1 |
| InChI | InChI=1S/C14H22N2O3/c1-10(2)16-8-12(17)9-19-13-5-3-11(4-6-13)7-14(15)18/h3-6,10,12,16-17H,7-9H2,1-2H3,(H2,15,18) |
| InChIKey | METKIMKYRPQLGS-UHFFFAOYSA-N |
| Wikipedia |
|---|
| Roles Classification |
|---|
| Chemical Roles: | environmental contaminant Any minor or unwanted substance introduced into the environment that can have undesired effects. Bronsted base A molecular entity capable of accepting a hydron from a donor (Brønsted acid). |
| Biological Roles: | xenobiotic A xenobiotic (Greek, xenos "foreign"; bios "life") is a compound that is foreign to a living organism. Principal xenobiotics include: drugs, carcinogens and various compounds that have been introduced into the environment by artificial means. sympatholytic agent Any compound which inhibits the postganglionic functioning of the sympathetic nervous system (SNS). beta-adrenergic antagonist An agent that binds to but does not activate β-adrenergic receptors thereby blocking the actions of endogenous or exogenous β-adrenergic agonists. β-Adrenergic antagonists are used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches and anxiety. |
| Applications: | hypoglycemic agent A drug which lowers the blood glucose level. antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. antidepressant Antidepressants are mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. anti-arrhythmia drug A drug used for the treatment or prevention of cardiac arrhythmias. Anti-arrhythmia drugs may affect the polarisation-repolarisation phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibres. bone density conservation agent An agent that inhibits bone resorption and/or favor bone mineralization and bone regeneration. Used to heal bone fractures and to treat bone diseases such as osteopenia and osteoporosis. antihypertensive agent Any drug used in the treatment of acute or chronic vascular hypertension regardless of pharmacological mechanism. cardiovascular drug A drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume. sympatholytic agent Any compound which inhibits the postganglionic functioning of the sympathetic nervous system (SNS). beta-adrenergic antagonist An agent that binds to but does not activate β-adrenergic receptors thereby blocking the actions of endogenous or exogenous β-adrenergic agonists. β-Adrenergic antagonists are used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches and anxiety. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| atenolol (CHEBI:2904) has role anti-arrhythmia drug (CHEBI:38070) |
| atenolol (CHEBI:2904) has role antidepressant (CHEBI:35469) |
| atenolol (CHEBI:2904) has role antihypertensive agent (CHEBI:35674) |
| atenolol (CHEBI:2904) has role antineoplastic agent (CHEBI:35610) |
| atenolol (CHEBI:2904) has role bone density conservation agent (CHEBI:50646) |
| atenolol (CHEBI:2904) has role cardiovascular drug (CHEBI:35554) |
| atenolol (CHEBI:2904) has role environmental contaminant (CHEBI:78298) |
| atenolol (CHEBI:2904) has role hypoglycemic agent (CHEBI:35526) |
| atenolol (CHEBI:2904) has role sympatholytic agent (CHEBI:66991) |
| atenolol (CHEBI:2904) has role xenobiotic (CHEBI:35703) |
| atenolol (CHEBI:2904) has role β-adrenergic antagonist (CHEBI:35530) |
| atenolol (CHEBI:2904) is a ethanolamines (CHEBI:23981) |
| atenolol (CHEBI:2904) is a monocarboxylic acid amide (CHEBI:29347) |
| atenolol (CHEBI:2904) is a propanolamine (CHEBI:35533) |
| Incoming Relation(s) |
| (R)-atenolol (CHEBI:55352) is a atenolol (CHEBI:2904) |
| esatenolol (CHEBI:31556) is a atenolol (CHEBI:2904) |
| IUPAC Name |
|---|
| 2-(4-{2-hydroxy-3-[(propan-2-yl)amino]propoxy}phenyl)acetamide |
| INNs | Source |
|---|---|
| atenolol | KEGG DRUG |
| atenololum | ChemIDplus |
| Synonyms | Source |
|---|---|
| 1-p-Carbamoylmethylphenoxy-3-isopropylamino-2-propanol | NIST Chemistry WebBook |
| 2-(p-(2-Hydroxy-3-(isopropylamino)propoxy)phenyl)acetamide | ChemIDplus |
| 4-(2-Hydroxy-3-((1-methylethyl)amino)propoxy)benzeneacetamide | ChemIDplus |
| C07AB03 | ChEMBL |
| ICI 66,082 | ChEMBL |
| ICI 66082 | ChEMBL |
| Brand Names | Source |
|---|---|
| Atenamin | ChEMBL |
| Atenix-100 | ChEMBL |
| Atenix-25 | ChEMBL |
| Atenix-50 | ChEMBL |
| Atenolol component of polycap | ChEMBL |
| Atenolol component of tenoretic | ChEMBL |
| Registry Numbers | Sources |
|---|---|
| Gmelin:2179742 | Gmelin |
| Reaxys:2739235 | Reaxys |
| CAS:29122-68-7 | KEGG DRUG |
| CAS:29122-68-7 | NIST Chemistry WebBook |
| CAS:29122-68-7 | ChemIDplus |
| CAS:29122-68-7 | DrugBank |
| Citations |
|---|