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CHEBI:2904 - atenolol
| Formula | C14H22N2O3 |
| Net Charge | 0 |
| Average Mass | 266.341 |
| Monoisotopic Mass | 266.16304 |
| SMILES | CC(C)NCC(O)COc1ccc(CC(N)=O)cc1 |
| InChI | InChI=1S/C14H22N2O3/c1-10(2)16-8-12(17)9-19-13-5-3-11(4-6-13)7-14(15)18/h3-6,10,12,16-17H,7-9H2,1-2H3,(H2,15,18) |
| InChIKey | METKIMKYRPQLGS-UHFFFAOYSA-N |
| Wikipedia |
|---|
| Roles Classification |
|---|
| Chemical Roles: | environmental contaminant Any minor or unwanted substance introduced into the environment that can have undesired effects. Bronsted base A molecular entity capable of accepting a hydron from a donor (Brønsted acid). |
| Biological Roles: | xenobiotic A xenobiotic (Greek, xenos "foreign"; bios "life") is a compound that is foreign to a living organism. Principal xenobiotics include: drugs, carcinogens and various compounds that have been introduced into the environment by artificial means. sympatholytic agent Any compound which inhibits the postganglionic functioning of the sympathetic nervous system (SNS). beta-adrenergic antagonist An agent that binds to but does not activate β-adrenergic receptors thereby blocking the actions of endogenous or exogenous β-adrenergic agonists. β-Adrenergic antagonists are used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches and anxiety. |
| Applications: | anti-arrhythmia drug A drug used for the treatment or prevention of cardiac arrhythmias. Anti-arrhythmia drugs may affect the polarisation-repolarisation phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibres. sympatholytic agent Any compound which inhibits the postganglionic functioning of the sympathetic nervous system (SNS). beta-adrenergic antagonist An agent that binds to but does not activate β-adrenergic receptors thereby blocking the actions of endogenous or exogenous β-adrenergic agonists. β-Adrenergic antagonists are used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches and anxiety. antihypertensive agent Any drug used in the treatment of acute or chronic vascular hypertension regardless of pharmacological mechanism. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| atenolol (CHEBI:2904) has role anti-arrhythmia drug (CHEBI:38070) |
| atenolol (CHEBI:2904) has role antihypertensive agent (CHEBI:35674) |
| atenolol (CHEBI:2904) has role environmental contaminant (CHEBI:78298) |
| atenolol (CHEBI:2904) has role sympatholytic agent (CHEBI:66991) |
| atenolol (CHEBI:2904) has role xenobiotic (CHEBI:35703) |
| atenolol (CHEBI:2904) has role β-adrenergic antagonist (CHEBI:35530) |
| atenolol (CHEBI:2904) is a ethanolamines (CHEBI:23981) |
| atenolol (CHEBI:2904) is a monocarboxylic acid amide (CHEBI:29347) |
| atenolol (CHEBI:2904) is a propanolamine (CHEBI:35533) |
| Incoming Relation(s) |
| (R)-atenolol (CHEBI:55352) is a atenolol (CHEBI:2904) |
| esatenolol (CHEBI:31556) is a atenolol (CHEBI:2904) |
| IUPAC Name |
|---|
| 2-(4-{2-hydroxy-3-[(propan-2-yl)amino]propoxy}phenyl)acetamide |
| INNs | Source |
|---|---|
| atenolol | KEGG DRUG |
| atenololum | ChemIDplus |
| Synonyms | Source |
|---|---|
| 1-p-Carbamoylmethylphenoxy-3-isopropylamino-2-propanol | NIST Chemistry WebBook |
| 2-(p-(2-Hydroxy-3-(isopropylamino)propoxy)phenyl)acetamide | ChemIDplus |
| 4-(2-Hydroxy-3-((1-methylethyl)amino)propoxy)benzeneacetamide | ChemIDplus |
| Registry Numbers | Sources |
|---|---|
| Gmelin:2179742 | Gmelin |
| Reaxys:2739235 | Reaxys |
| CAS:29122-68-7 | KEGG DRUG |
| CAS:29122-68-7 | DrugBank |
| CAS:29122-68-7 | ChemIDplus |
| CAS:29122-68-7 | NIST Chemistry WebBook |
| Citations |
|---|