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CHEBI:31460 - desferrioxamine B mesylate

ChEBI IDCHEBI:31460
ChEBI Namedesferrioxamine B mesylate
Stars
DefinitionA methanesulfonate salt obtained by reaction of desferrioxamine B with one molar equivalent of methanesulfonic acid. It is an iron-chelating medicine used to remove excess iron from the body. It binds to iron in the blood, which is then passed out in the urine.
Last Modified27 May 2021
DownloadsMolfile
FormulaH.C25H48N6O8.CH3O3S
Net Charge0
Average Mass656.800
Monoisotopic Mass656.34148
SMILESCC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCN.CS(=O)(=O)[O-].[H+]
InChIInChI=1S/C25H48N6O8.CH4O3S/c1-21(32)29(37)18-9-3-6-16-27-22(33)12-14-25(36)31(39)20-10-4-7-17-28-23(34)11-13-24(35)30(38)19-8-2-5-15-26;1-5(2,3)4/h37-39H,2-20,26H2,1H3,(H,27,33)(H,28,34);1H3,(H,2,3,4)
InChIKeyIDDIJAWJANBQLJ-UHFFFAOYSA-N
Roles Classification
Chemical Role:
Biological Role:
ferroptosis inhibitor  Any substance that inhibits the process of ferroptosis (a type of programmed cell death dependent on iron and characterized by the accumulation of lipid peroxides) in organisms.
Application:
antidote  Any protective agent counteracting or neutralizing the action of poisons.
ChEBI Ontology
Outgoing Relation(s)
desferrioxamine B mesylate (CHEBI:31460) has part desferrioxamine B (CHEBI:4356)
desferrioxamine B mesylate (CHEBI:31460) has role antidote (CHEBI:50247)
desferrioxamine B mesylate (CHEBI:31460) has role ferroptosis inhibitor (CHEBI:173084)
desferrioxamine B mesylate (CHEBI:31460) has role iron chelator (CHEBI:38157)
desferrioxamine B mesylate (CHEBI:31460) is a methanesulfonate salt (CHEBI:38037)
IUPAC Name 
N'-{5-[acetyl(hydroxy)amino]pentyl}-N-(5-{4-[(5-aminopentyl)(hydroxy)amino]-4-oxobutanamido}pentyl)-N-hydroxybutanediamide methanesulfonate
Synonyms  Source
Deferoxamine B mesylateChemIDplus
Deferoxamine mesylateChemIDplus
Deferoxamine methanesulfonateChemIDplus
Desferrioxamine mesylateChemIDplus
Desferrioxamine methanesulfonateChemIDplus
desferrioxamine mesilateDrugBank
Brand Names  Source
DesferalDrugBank
DesferinDrugBank
Manual XrefsDatabases
DBSALT000964DrugBank
D01186KEGG DRUG
CPD-8951MetaCyc
Registry NumbersSources
Beilstein:6047788Beilstein
CAS:138-14-7ChemIDplus
Citations