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CHEBI:31430 - conivaptan hydrochloride

ChEBI IDCHEBI:31430
ChEBI Nameconivaptan hydrochloride
Stars
DefinitionThe hydrochloride salt of conivaptan. It is an antagonist for two of the three types of arginine vasopressin (AVP) receptors, V1a and V2, and is used for the treatment of hyponatraemia (low blood sodium levels) caused by syndrome of inappropriate antidiuretic hormone (SIADH).
Last Modified20 February 2023
DownloadsMolfile
FormulaC32H26N4O2.HCl
Net Charge0
Average Mass535.047
Monoisotopic Mass534.18225
SMILESCc1nc2c(n1)-c1ccccc1N(C(=O)c1ccc(NC(=O)c3ccccc3-c3ccccc3)cc1)CC2.Cl
InChIInChI=1S/C32H26N4O2.ClH/c1-21-33-28-19-20-36(29-14-8-7-13-27(29)30(28)34-21)32(38)23-15-17-24(18-16-23)35-31(37)26-12-6-5-11-25(26)22-9-3-2-4-10-22;/h2-18H,19-20H2,1H3,(H,33,34)(H,35,37);1H
InChIKeyBTYHAFSDANBVMJ-UHFFFAOYSA-N
Roles Classification
Biological Role:
vasopressin receptor antagonist  Any drug which blocks vasopressin receptors.
Applications:
vasopressin receptor antagonist  Any drug which blocks vasopressin receptors.
aquaretic  A class of diuretics which promote aquaresis (the excretion of water without electrolyte loss).
ChEBI Ontology
Outgoing Relation(s)
conivaptan hydrochloride (CHEBI:31430) has part conivaptan (CHEBI:681850)
conivaptan hydrochloride (CHEBI:31430) has role aquaretic (CHEBI:194423)
conivaptan hydrochloride (CHEBI:31430) has role vasopressin receptor antagonist (CHEBI:59680)
conivaptan hydrochloride (CHEBI:31430) is a hydrochloride (CHEBI:36807)
IUPAC Name 
N-{4-[(2-methyl-4,5-dihydroimidazo[4,5-d][1]benzazepin-6(1H)-yl)carbonyl]phenyl}biphenyl-2-carboxamide hydrochloride
Synonyms  Source
conivaptan HClChemIDplus
4'-((4,5-dihydro-2-methylimidazo(4,5-d)(1)benzazepin-6(1H)-yl)carbonyl)-2-biphenylcarboxanilide monohydrochlorideChemIDplus
Manual XrefsDatabases
D01236KEGG DRUG
DB00872DrugBank
Registry NumbersSources
Beilstein:8667691Beilstein
CAS:168626-94-6KEGG DRUG
CAS:168626-94-6ChemIDplus