ciclopirox olamine (CHEBI:31398)

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CHEBI:31398 - ciclopirox olamine

ChEBI ID	CHEBI:31398
ChEBI Name	ciclopirox olamine
Stars
Definition	The ethanolamine salt of ciclopirox. A broad spectrum antigfungal agent, it also exhibits antibacterial activity against many Gram-positive and Gram-negative bacteria, and has anti-inflammatory properties. It is used a a topical treatment of fungal skin and nail infections.
Secondary ChEBI IDs	CHEBI:489955, CHEBI:566263
Last Modified	20 September 2021
Downloads	Molfile

Formula	C12H16NO2.C2H8NO
Net Charge	0
Average Mass	268.357
Monoisotopic Mass	268.17869
SMILES	Cc1cc(C2CCCCC2)n([O-])c(=O)c1.[NH3+]CCO
InChI	InChI=1S/C12H16NO2.C2H7NO/c1-9-7-11(13(15)12(14)8-9)10-5-3-2-4-6-10;3-1-2-4/h7-8,10H,2-6H2,1H3;4H,1-3H2/q-1;/p+1
InChIKey	HKUKJIQHPXYJTP-UHFFFAOYSA-O

Roles Classification

Biological Roles:

ferroptosis inhibitor Any substance that inhibits the process of ferroptosis (a type of programmed cell death dependent on iron and characterized by the accumulation of lipid peroxides) in organisms.

antibacterial agent A substance (or active part thereof) that kills or slows the growth of bacteria.

antifungal drug Any antifungal agent used to prevent or treat fungal infections in humans or animals.

Applications:

antiseborrheic A drug or agent applied to the skin to control seborrhea or seborrheic dermatitis.

geroprotector Any compound that supports healthy aging, slows the biological aging process, or extends lifespan.

antifungal drug Any antifungal agent used to prevent or treat fungal infections in humans or animals.

ChEBI Ontology

Outgoing Relation(s)
	ciclopirox olamine (CHEBI:31398) has part ciclopirox (CHEBI:453011)
	ciclopirox olamine (CHEBI:31398) has part ethanolaminium(1+) (CHEBI:57603)
	ciclopirox olamine (CHEBI:31398) has role antibacterial agent (CHEBI:33282)
	ciclopirox olamine (CHEBI:31398) has role antiseborrheic (CHEBI:59010)
	ciclopirox olamine (CHEBI:31398) has role ferroptosis inhibitor (CHEBI:173084)
	ciclopirox olamine (CHEBI:31398) has role geroprotector (CHEBI:176497)
	ciclopirox olamine (CHEBI:31398) is a hydroxypyridone antifungal drug (CHEBI:87130)
	ciclopirox olamine (CHEBI:31398) is a organoammonium salt (CHEBI:46850)

IUPAC Name
2-hydroxyethanaminium 6-cyclohexyl-4-methyl-2-oxopyridin-1(2H)-olate

Synonyms	Source
ciclopirox ethanolamine salt	ChemIDplus
HOE 296	ChemIDplus
HOE-296	DrugBank

Brand Names	Source
Batrafen	ChemIDplus
Brumixol	ChemIDplus
Loprox	ChemIDplus
Micoxolamina	ChemIDplus
Mycoster	ChemIDplus

Manual Xrefs	Databases
D01364	KEGG DRUG
DBSALT001147	DrugBank

Registry Numbers	Sources
Beilstein:6494273	Beilstein
CAS:41621-49-2	KEGG DRUG
CAS:41621-49-2	ChemIDplus

Citations