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CHEBI:31303 - bromhexine hydrochloride

ChEBI IDCHEBI:31303
ChEBI Namebromhexine hydrochloride
Stars
DefinitionA hydrochloride resulting from the reaction of equimolar amounts of bromhexine and hydrogen chloride. It is used as a mucolytic for the treatment of respiratory disorders associated with productive cough (i.e. a cough characterised by the production of sputum).
Last Modified21 January 2014
DownloadsMolfile
FormulaC14H20Br2N2.HCl
Net Charge0
Average Mass412.597
Monoisotopic Mass409.97600
SMILESCN(Cc1cc(Br)cc(Br)c1N)C1CCCCC1.Cl
InChIInChI=1S/C14H20Br2N2.ClH/c1-18(12-5-3-2-4-6-12)9-10-7-11(15)8-13(16)14(10)17;/h7-8,12H,2-6,9,17H2,1H3;1H
InChIKeyUCDKONUHZNTQPY-UHFFFAOYSA-N
Roles Classification
Application:
mucolytic  A compound that alters the structure of mucus so as to decrease its viscosity and thereby facilitate its removal by ciliary action and expectoration. Compare with antitussives, which suppress the cough reflex, and expectorants, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing.
ChEBI Ontology
Outgoing Relation(s)
bromhexine hydrochloride (CHEBI:31303) has part bromhexine(1+) (CHEBI:77040)
bromhexine hydrochloride (CHEBI:31303) has role mucolytic (CHEBI:77034)
bromhexine hydrochloride (CHEBI:31303) is a hydrochloride (CHEBI:36807)
IUPAC Name 
2,4-dibromo-6-{[cyclohexyl(methyl)amino]methyl}aniline hydrochloride
Synonyms  Source
N-(2-amino-3,5-dibromobenzyl)-N-methylcyclohexanaminium chlorideIUPAC
2-amino-N-cyclohexyl-3,5-dibromo-N-methylbenzylamine hydrochlorideChemIDplus
3,5-dibromo-Nα-cyclohexyl-Nα-methyltoluene-α,2-diamine monohydrochlorideChemIDplus
bromhexine chlorideChemIDplus
N-cyclohexyl-N-methyl-(2-amino-3,5-dibromobenzyl)ammonium chlorideChemIDplus
bromhexine HClChemIDplus
Brand Names  Source
BroncokinChemIDplus
AuxitChemIDplus
ViscolytChemIDplus
OphtolsolChEBI
QuentanChEBI
Manual XrefsDatabases
D01778KEGG DRUG
CN101817754Patent
1786VSDB
Registry NumbersSources
Reaxys:4848376Reaxys
CAS:611-75-6ChemIDplus
Citations