betamethasone dipropionate (CHEBI:31276)

Example searches: iron*, InChI=1S/CH4O/c1-2/h2H,1H3, caffeine | Advanced Search

CHEBI:31276 - betamethasone dipropionate

ChEBI ID	CHEBI:31276
ChEBI Name	betamethasone dipropionate
Stars
Definition	A steroid ester that is betamethasone in which the hydroxy hydrogens at positions 17 and 21 are replaced by propanoyl groups. It is used in combination with calcipotriene hydrate, a synthetic vitamin D analogue, for the topical treatment of plaque psoriasis in adult patients.
Last Modified	22 February 2017
Downloads	Molfile

Formula	C28H37FO7
Net Charge	0
Average Mass	504.595
Monoisotopic Mass	504.25233
SMILES	[H][C@@]12C[C@H](C)[C@](OC(=O)CC)(C(=O)COC(=O)CC)[C@@]1(C)C[C@H](O)[C@@]1(F)[C@@]2([H])CCC2=CC(=O)C=C[C@@]21C
InChI	InChI=1S/C28H37FO7/c1-6-23(33)35-15-22(32)28(36-24(34)7-2)16(3)12-20-19-9-8-17-13-18(30)10-11-25(17,4)27(19,29)21(31)14-26(20,28)5/h10-11,13,16,19-21,31H,6-9,12,14-15H2,1-5H3/t16-,19-,20-,21-,25-,26-,27-,28-/m0/s1
InChIKey	CIWBQSYVNNPZIQ-XYWKZLDCSA-N

Wikipedia

Roles Classification

Applications:

dermatologic drug A drug used to treat or prevent skin disorders or for the routine care of skin.

antifibrotic agent Any agent which acts to reduce fibrosis.

antiinfective agent A substance used in the prophylaxis or therapy of infectious diseases.

gout suppressant A drug that increases uric acid excretion by the kidney (uricosuric drug), decreases uric acid production (antihyperuricemic), or alleviates the pain and inflammation of acute attacks of gout.

antipsoriatic A drug used to treat psoriasis.

ChEBI Ontology

Outgoing Relation(s)
	betamethasone dipropionate (CHEBI:31276) has functional parent betamethasone (CHEBI:3077)
	betamethasone dipropionate (CHEBI:31276) has role antifibrotic agent (CHEBI:233423)
	betamethasone dipropionate (CHEBI:31276) has role antiinfective agent (CHEBI:35441)
	betamethasone dipropionate (CHEBI:31276) has role antipsoriatic (CHEBI:50748)
	betamethasone dipropionate (CHEBI:31276) has role dermatologic drug (CHEBI:50177)
	betamethasone dipropionate (CHEBI:31276) has role gout suppressant (CHEBI:35845)
	betamethasone dipropionate (CHEBI:31276) is a 11β-hydroxy steroid (CHEBI:35346)
	betamethasone dipropionate (CHEBI:31276) is a 20-oxo steroid (CHEBI:36885)
	betamethasone dipropionate (CHEBI:31276) is a 3-oxo-Δ¹,Δ⁴-steroid (CHEBI:77166)
	betamethasone dipropionate (CHEBI:31276) is a fluorinated steroid (CHEBI:50830)
	betamethasone dipropionate (CHEBI:31276) is a propanoate ester (CHEBI:36243)
	betamethasone dipropionate (CHEBI:31276) is a steroid ester (CHEBI:47880)
Incoming Relation(s)
Incoming Relation(s)	Enstilar (CHEBI:90855) has part betamethasone dipropionate (CHEBI:31276)

IUPAC Name
9-fluoro-11β-hydroxy-16β-methyl-3,20-dioxopregna-1,4-diene-17,21-diyl dipropanoate

Synonyms	Source
9-Fluoro-11β,17,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione-17,21-dipropionate	ChemIDplus
Betamethasone 17,21-dipropionate	ChemIDplus
Betamethasone (as dipropionate)	ChEMBL
Diprospan	ChEMBL
Maxivate	ChEMBL
NSC-758415	ChEMBL

Brand Names	Source
Alphatrex	ChEMBL
Betamethasone dipropionate component of enstilar	ChEMBL
Betamethasone dipropionate component of leo-90100	ChEMBL
Betamethasone dipropionate component of lotrisone	ChEMBL
Betamethasone dipropionate component of taclonex	ChEMBL
Betamethasone dipropionate component of wynzora	ChEMBL

Manual Xrefs	Databases
353	DrugCentral
Betamethasone_Dipropionate	Wikipedia
D01637	KEGG DRUG
DB00443	DrugBank

Registry Numbers	Sources
Reaxys:3638108	Reaxys
CAS:5593-20-4	ChemIDplus

Citations