betamethasone dipropionate (CHEBI:31276)

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CHEBI:31276 - betamethasone dipropionate

ChEBI ID	CHEBI:31276
ChEBI Name	betamethasone dipropionate
Stars
Definition	A steroid ester that is betamethasone in which the hydroxy hydrogens at positions 17 and 21 are replaced by propanoyl groups. It is used in combination with calcipotriene hydrate, a synthetic vitamin D analogue, for the topical treatment of plaque psoriasis in adult patients.
Last Modified	22 February 2017
Downloads	Molfile

Formula	C28H37FO7
Net Charge	0
Average Mass	504.595
Monoisotopic Mass	504.25233
SMILES	[H][C@@]12C[C@H](C)[C@](OC(=O)CC)(C(=O)COC(=O)CC)[C@@]1(C)C[C@H](O)[C@@]1(F)[C@@]2([H])CCC2=CC(=O)C=C[C@@]21C
InChI	InChI=1S/C28H37FO7/c1-6-23(33)35-15-22(32)28(36-24(34)7-2)16(3)12-20-19-9-8-17-13-18(30)10-11-25(17,4)27(19,29)21(31)14-26(20,28)5/h10-11,13,16,19-21,31H,6-9,12,14-15H2,1-5H3/t16-,19-,20-,21-,25-,26-,27-,28-/m0/s1
InChIKey	CIWBQSYVNNPZIQ-XYWKZLDCSA-N

Wikipedia

Roles Classification

Applications:

antipsoriatic A drug used to treat psoriasis.

dermatologic drug A drug used to treat or prevent skin disorders or for the routine care of skin.

gout suppressant A drug that increases uric acid excretion by the kidney (uricosuric drug), decreases uric acid production (antihyperuricemic), or alleviates the pain and inflammation of acute attacks of gout.

antifibrotic agent Any agent which acts to reduce fibrosis.

antiinfective agent A substance used in the prophylaxis or therapy of infectious diseases.

ChEBI Ontology

Outgoing Relation(s)
	betamethasone dipropionate (CHEBI:31276) has functional parent betamethasone (CHEBI:3077)
	betamethasone dipropionate (CHEBI:31276) has role antifibrotic agent (CHEBI:233423)
	betamethasone dipropionate (CHEBI:31276) has role antiinfective agent (CHEBI:35441)
	betamethasone dipropionate (CHEBI:31276) has role antipsoriatic (CHEBI:50748)
	betamethasone dipropionate (CHEBI:31276) has role dermatologic drug (CHEBI:50177)
	betamethasone dipropionate (CHEBI:31276) has role gout suppressant (CHEBI:35845)
	betamethasone dipropionate (CHEBI:31276) is a 11β-hydroxy steroid (CHEBI:35346)
	betamethasone dipropionate (CHEBI:31276) is a 20-oxo steroid (CHEBI:36885)
	betamethasone dipropionate (CHEBI:31276) is a 3-oxo-Δ¹,Δ⁴-steroid (CHEBI:77166)
	betamethasone dipropionate (CHEBI:31276) is a fluorinated steroid (CHEBI:50830)
	betamethasone dipropionate (CHEBI:31276) is a propanoate ester (CHEBI:36243)
	betamethasone dipropionate (CHEBI:31276) is a steroid ester (CHEBI:47880)
Incoming Relation(s)
Incoming Relation(s)	Enstilar (CHEBI:90855) has part betamethasone dipropionate (CHEBI:31276)

IUPAC Name
9-fluoro-11β-hydroxy-16β-methyl-3,20-dioxopregna-1,4-diene-17,21-diyl dipropanoate

Synonyms	Source
9-Fluoro-11β,17,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione-17,21-dipropionate	ChemIDplus
Betamethasone 17,21-dipropionate	ChemIDplus
Betamethasone (as dipropionate)	ChEMBL
Diprospan	ChEMBL
Maxivate	ChEMBL
NSC-758415	ChEMBL

Brand Names	Source
Alphatrex	ChEMBL
Betamethasone dipropionate component of enstilar	ChEMBL
Betamethasone dipropionate component of leo-90100	ChEMBL
Betamethasone dipropionate component of lotrisone	ChEMBL
Betamethasone dipropionate component of taclonex	ChEMBL
Betamethasone dipropionate component of wynzora	ChEMBL

Manual Xrefs	Databases
353	DrugCentral
Betamethasone_Dipropionate	Wikipedia
D01637	KEGG DRUG
DB00443	DrugBank

Registry Numbers	Sources
Reaxys:3638108	Reaxys
CAS:5593-20-4	ChemIDplus

Citations