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CHEBI:3077 - betamethasone
| Formula | C22H29FO5 |
| Net Charge | 0 |
| Average Mass | 392.467 |
| Monoisotopic Mass | 392.19990 |
| SMILES | [H][C@@]12C[C@H](C)[C@](O)(C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]1(F)[C@@]2([H])CCC2=CC(=O)C=C[C@@]21C |
| InChI | InChI=1S/C22H29FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15-,16-,17-,19-,20-,21-,22-/m0/s1 |
| InChIKey | UREBDLICKHMUKA-DVTGEIKXSA-N |
| Wikipedia |
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| Roles Classification |
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| Biological Roles: | immunosuppressive agent An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response. analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. hormone Originally referring to an endogenous compound that is formed in specialized organ or group of cells and carried to another organ or group of cells, in the same organism, upon which it has a specific regulatory function, the term is now commonly used to include non-endogenous, semi-synthetic and fully synthetic analogues of such compounds. |
| Applications: | antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. anti-ulcer drug One of various classes of drugs with different action mechanisms used to treat or ameliorate peptic ulcer or irritation of the gastrointestinal tract. immunosuppressive agent An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response. anti-inflammatory drug A substance that reduces or suppresses inflammation. ophthalmology drug Any compound used for the treatment of eye conditions or eye diseases. antipsoriatic A drug used to treat psoriasis. nasal decongestant A drug used to relieve nasal congestion in the upper respiratory tract. anti-asthmatic agent Any compound that has anti-asthmatic effects. antitussive An agent that suppresses cough. Antitussives have a central or a peripheral action on the cough reflex, or a combination of both. Compare with expectorants, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing, and mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration. analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. gout suppressant A drug that increases uric acid excretion by the kidney (uricosuric drug), decreases uric acid production (antihyperuricemic), or alleviates the pain and inflammation of acute attacks of gout. dermatologic drug A drug used to treat or prevent skin disorders or for the routine care of skin. antiglaucoma drug Any drug which can be used to prevent or alleviate glaucoma, a disease in which the optic nerve is damaged, resulting in progressive, irreversible loss of vision. It is often, though not always, associated with increased pressure of the fluid in the eye. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| betamethasone (CHEBI:3077) has parent hydride pregnane (CHEBI:8386) |
| betamethasone (CHEBI:3077) has role analgesic (CHEBI:35480) |
| betamethasone (CHEBI:3077) has role anti-asthmatic agent (CHEBI:65023) |
| betamethasone (CHEBI:3077) has role anti-inflammatory drug (CHEBI:35472) |
| betamethasone (CHEBI:3077) has role anti-ulcer drug (CHEBI:49201) |
| betamethasone (CHEBI:3077) has role antiglaucoma drug (CHEBI:39456) |
| betamethasone (CHEBI:3077) has role antineoplastic agent (CHEBI:35610) |
| betamethasone (CHEBI:3077) has role antipsoriatic (CHEBI:50748) |
| betamethasone (CHEBI:3077) has role antitussive (CHEBI:51177) |
| betamethasone (CHEBI:3077) has role dermatologic drug (CHEBI:50177) |
| betamethasone (CHEBI:3077) has role gout suppressant (CHEBI:35845) |
| betamethasone (CHEBI:3077) has role immunosuppressive agent (CHEBI:35705) |
| betamethasone (CHEBI:3077) has role nasal decongestant (CHEBI:77715) |
| betamethasone (CHEBI:3077) has role ophthalmology drug (CHEBI:66981) |
| betamethasone (CHEBI:3077) is a 11β-hydroxy steroid (CHEBI:35346) |
| betamethasone (CHEBI:3077) is a 17α-hydroxy steroid (CHEBI:35342) |
| betamethasone (CHEBI:3077) is a 20-oxo steroid (CHEBI:36885) |
| betamethasone (CHEBI:3077) is a 21-hydroxy steroid (CHEBI:35344) |
| betamethasone (CHEBI:3077) is a 3-oxo-Δ1,Δ4-steroid (CHEBI:77166) |
| betamethasone (CHEBI:3077) is a fluorinated steroid (CHEBI:50830) |
| betamethasone (CHEBI:3077) is a glucocorticoid (CHEBI:24261) |
| betamethasone (CHEBI:3077) is a primary α-hydroxy ketone (CHEBI:139590) |
| betamethasone (CHEBI:3077) is a tertiary α-hydroxy ketone (CHEBI:139592) |
| Incoming Relation(s) |
| betamethasone acetate (CHEBI:31275) has functional parent betamethasone (CHEBI:3077) |
| betamethasone acibutate (CHEBI:50894) has functional parent betamethasone (CHEBI:3077) |
| betamethasone dipropionate (CHEBI:31276) has functional parent betamethasone (CHEBI:3077) |
| betamethasone phosphate (CHEBI:68603) has functional parent betamethasone (CHEBI:3077) |
| betamethasone valerate (CHEBI:31277) has functional parent betamethasone (CHEBI:3077) |
| IUPAC Name |
|---|
| 9-fluoro-11β,17,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione |
| INNs | Source |
|---|---|
| betametasona | ChEBI |
| betamethasone | ChEBI |
| bétaméthasone | ChEBI |
| betamethasonum | ChEBI |
| Synonyms | Source |
|---|---|
| 16β-Methyl-1,4-pregnadiene-9α-fluoro-11β,17α,21-triol-3,20-dione | ChemIDplus |
| 9-Fluoro-16β-methylprednisolone | ChemIDplus |
| 9α-Fluoro-16β-methylprednisolone | ChemIDplus |
| Betadexamethasone | ChemIDplus |
| beta-Methasone alcohol | ChemIDplus |
| Flubenisolone | ChEMBL |
| Brand Names | Source |
|---|---|
| Betasolan | ChEMBL |
| Betnelan | ChEMBL |
| Celestone | ChEMBL |
| Citations |
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