CHEBI:3112 - biperiden

ChEBI IDCHEBI:3112
ChEBI Namebiperiden
Stars
DefinitionA member of the class of piperidines that is N-propylpiperidine in which the methyl hydrogens have been replaced by hydroxy, phenyl, and 5-norbornen-2-yl groups. A muscarinic antagonist affecting both the central and peripheral nervous systems, it is used in the treatment of all forms of Parkinson's disease.
Secondary ChEBI IDCHEBI:251063
Last Modified20 April 2017
DownloadsMolfile
FormulaC21H29NO
Net Charge0
Average Mass311.469
Monoisotopic Mass311.22491
SMILESOC(CCN1CCCCC1)(c1ccccc1)C1CC2C=CC1C2
InChIInChI=1S/C21H29NO/c23-21(19-7-3-1-4-8-19,11-14-22-12-5-2-6-13-22)20-16-17-9-10-18(20)15-17/h1,3-4,7-10,17-18,20,23H,2,5-6,11-16H2
InChIKeyYSXKPIUOCJLQIE-UHFFFAOYSA-N
Wikipedia
Roles Classification
Chemical Role:
Bronsted base  A molecular entity capable of accepting a hydron from a donor (Brønsted acid).
Biological Roles:
parasympatholytic  Any cholinergic antagonist that inhibits the actions of the parasympathetic nervous system. The major group of drugs used therapeutically for this purpose is the muscarinic antagonists.
muscarinic antagonist  A drug that binds to but does not activate muscarinic cholinergic receptors, thereby blocking the actions of endogenous acetylcholine or exogenous agonists.
Applications:
parasympatholytic  Any cholinergic antagonist that inhibits the actions of the parasympathetic nervous system. The major group of drugs used therapeutically for this purpose is the muscarinic antagonists.
muscarinic antagonist  A drug that binds to but does not activate muscarinic cholinergic receptors, thereby blocking the actions of endogenous acetylcholine or exogenous agonists.
antiparkinson drug  A drug used in the treatment of Parkinson's disease.
antidyskinesia agent  Any compound which can be used to treat or alleviate the symptoms of dyskinesia.
antidote to sarin poisoning  A role borne by a molecule that acts to counteract or neutralise the nerve agent sarin.
ChEBI Ontology
Outgoing Relation(s)
biperiden (CHEBI:3112) has role antidote to sarin poisoning (CHEBI:136860)
biperiden (CHEBI:3112) has role antidyskinesia agent (CHEBI:66956)
biperiden (CHEBI:3112) has role antiparkinson drug (CHEBI:48407)
biperiden (CHEBI:3112) has role muscarinic antagonist (CHEBI:48876)
biperiden (CHEBI:3112) has role parasympatholytic (CHEBI:50370)
biperiden (CHEBI:3112) is a piperidines (CHEBI:26151)
biperiden (CHEBI:3112) is a tertiary alcohol (CHEBI:26878)
biperiden (CHEBI:3112) is a tertiary amino compound (CHEBI:50996)
Incoming Relation(s)
biperiden hydrochloride (CHEBI:59171) has part biperiden (CHEBI:3112)
IUPAC Name 
1-(bicyclo[2.2.1]hept-5-en-2-yl)-1-phenyl-3-(piperidin-1-yl)propan-1-ol
INNs  Source
biperidenChemIDplus
biperideneChemIDplus
biperidenoChemIDplus
biperidenumChemIDplus
Synonyms  Source
1-Bicyclo[2.2.1]hept-5-en-2-yl-1-phenyl-3-piperidin-1-yl-propan-1-olChEMBL
α-5-norbornen-2-yl-α-phenyl-1-piperidinepropanolChEBI
α-bicyclo[2.2.1]hept-5-en-2-yl-α-phenyl-1-piperidinepropanolChEBI
Manual XrefsDatabases
374DrugCentral
BiperidenWikipedia
C07941KEGG COMPOUND
D00779KEGG DRUG
DB00810DrugBank
LSM-1235LINCS
US2789110Patent
Registry NumbersSources
Beilstein:290038Beilstein
CAS:514-65-8NIST Chemistry WebBook
CAS:514-65-8ChemIDplus
Citations