CHEBI:30413 - heme

ChEBI IDCHEBI:30413
ChEBI Nameheme
Stars
DefinitionA heme is any tetrapyrrolic chelate of iron.
Secondary ChEBI IDsCHEBI:14386, CHEBI:24491
Last Modified18 October 2016
SubmitterKirill Degtyarenko
Species of MetaboliteComponentSourceComments
Homo sapiens (ncbitaxon:9606) - PubMed (21886157)
Roles Classification
Biological Roles:
prosthetic group  A tightly bound, specific nonpolypeptide unit in a protein determining and involved in its biological activity.
metabolite  Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
cofactor  An organic molecule or ion (usually a metal ion) that is required by an enzyme for its activity. It may be attached either loosely (coenzyme) or tightly (prosthetic group).
ChEBI Ontology
Outgoing Relation(s)
heme (CHEBI:30413) has role metabolite (CHEBI:25212)
heme (CHEBI:30413) has role prosthetic group (CHEBI:26348)
heme (CHEBI:30413) is a iron coordination entity (CHEBI:33892)
heme (CHEBI:30413) is a metalloporphyrin (CHEBI:25216)
heme (CHEBI:30413) is a metallotetrapyrrole (CHEBI:33909)
Incoming Relation(s)
hemoprotein (CHEBI:35137) has part heme (CHEBI:30413)
12,18-didecarboxysirohaem (CHEBI:132253) is a heme (CHEBI:30413)
alpha-oxyprotohemin IX (CHEBI:22465) is a heme (CHEBI:30413)
etiohemin I (CHEBI:24008) is a heme (CHEBI:30413)
ferriheme (CHEBI:38574) is a heme (CHEBI:30413)
ferroheme (CHEBI:38573) is a heme (CHEBI:30413)
heme a (CHEBI:24479) is a heme (CHEBI:30413)
heme b (CHEBI:26355) is a heme (CHEBI:30413)
heme o (CHEBI:24480) is a heme (CHEBI:30413)
heme-amino acid (CHEBI:24485) is a heme (CHEBI:30413)
heme-thiolate prosthetic group (CHEBI:36073) is a heme (CHEBI:30413)
siroheme (CHEBI:28599) is a heme (CHEBI:30413)
siroheme(8−) (CHEBI:60052) is a heme (CHEBI:30413)
IUPAC Names 
heme
hemes
Synonyms  Source
haemIUPAC
hæmChEBI
haemeIUPAC
HämChEBI
hemIUPAC
hèmeIUPAC
UniProt Name  Source
hemeUniProt
Manual XrefsDatabases
C00032KEGG COMPOUND
DB03014DrugBank