EMBL-EBI | Chemical Biology Resources | ChEBI
Example searches: iron*, InChI=1S/CH4O/c1-2/h2H,1H3, caffeine | Advanced Search
CHEBI:2979 - baicalein
| Formula | C15H10O5 |
| Net Charge | 0 |
| Average Mass | 270.240 |
| Monoisotopic Mass | 270.05282 |
| SMILES | O=c1cc(-c2ccccc2)oc2cc(O)c(O)c(O)c12 |
| InChI | InChI=1S/C15H10O5/c16-9-6-11(8-4-2-1-3-5-8)20-12-7-10(17)14(18)15(19)13(9)12/h1-7,17-19H |
| InChIKey | FXNFHKRTJBSTCS-UHFFFAOYSA-N |
| Wikipedia |
|---|
| Species of Metabolite | Component | Source | Comments |
|---|---|---|---|
| Lepisorus ussuriensis (ncbitaxon:699700) | whole plant (BTO:0001461) | PubMed (26569039) |
| Roles Classification |
|---|
| Chemical Roles: | antioxidant A substance that opposes oxidation or inhibits reactions brought about by dioxygen or peroxides. radical scavenger A role played by a substance that can react readily with, and thereby eliminate, radicals. |
| Biological Roles: | plant metabolite Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms. antibacterial agent A substance (or active part thereof) that kills or slows the growth of bacteria. antifungal agent An antimicrobial agent that destroys fungi by suppressing their ability to grow or reproduce. apoptosis inducer Any substance that induces the process of apoptosis (programmed cell death) in multi-celled organisms. prostaglandin antagonist A compound that inhibits the action of prostaglandins. EC 3.4.21.26 (prolyl oligopeptidase) inhibitor Any EC 3.4.21.* (serine endopeptidase) inhibitor that interferes with the action of prolyl oligopeptidase (EC 3.4.21.26). ferroptosis inhibitor Any substance that inhibits the process of ferroptosis (a type of programmed cell death dependent on iron and characterized by the accumulation of lipid peroxides) in organisms. hormone antagonist A chemical substance which inhibits the function of the endocrine glands, the biosynthesis of their secreted hormones, or the action of hormones upon their specific sites. EC 1.13.11.31 (arachidonate 12-lipoxygenase) inhibitor A lipoxygenase inhibitor that interferes with the action of arachidonate 12-lipoxygenase (EC 1.13.11.31). EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor A lipoxygenase inhibitor that interferes with the action of arachidonate 15-lipoxygenase (EC 1.13.11.33). EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor An EC 3.4.22.* (cysteine endopeptidase) inhibitor that interferes with the action of SARS coronavirus main proteinase (EC 3.4.22.69). antiviral agent A substance that destroys or inhibits replication of viruses. EC 4.1.1.17 (ornithine decarboxylase) inhibitor An EC 4.1.1.* (carboxy-lyase) inhibitor that interferes with the action of ornithine decarboxylase (EC 4.1.1.17). anticoronaviral agent Any antiviral agent which inhibits the activity of coronaviruses. |
| Applications: | geroprotector Any compound that supports healthy aging, slows the biological aging process, or extends lifespan. prostaglandin antagonist A compound that inhibits the action of prostaglandins. angiogenesis inhibitor An agent and endogenous substances that antagonize or inhibit the development of new blood vessels. hormone antagonist A chemical substance which inhibits the function of the endocrine glands, the biosynthesis of their secreted hormones, or the action of hormones upon their specific sites. antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. anti-inflammatory agent Any compound that has anti-inflammatory effects. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| baicalein (CHEBI:2979) has role angiogenesis inhibitor (CHEBI:48422) |
| baicalein (CHEBI:2979) has role anti-inflammatory agent (CHEBI:67079) |
| baicalein (CHEBI:2979) has role antibacterial agent (CHEBI:33282) |
| baicalein (CHEBI:2979) has role anticoronaviral agent (CHEBI:149553) |
| baicalein (CHEBI:2979) has role antifungal agent (CHEBI:35718) |
| baicalein (CHEBI:2979) has role antineoplastic agent (CHEBI:35610) |
| baicalein (CHEBI:2979) has role antioxidant (CHEBI:22586) |
| baicalein (CHEBI:2979) has role antiviral agent (CHEBI:22587) |
| baicalein (CHEBI:2979) has role apoptosis inducer (CHEBI:68495) |
| baicalein (CHEBI:2979) has role EC 1.13.11.31 (arachidonate 12-lipoxygenase) inhibitor (CHEBI:64995) |
| baicalein (CHEBI:2979) has role EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor (CHEBI:64996) |
| baicalein (CHEBI:2979) has role EC 3.4.21.26 (prolyl oligopeptidase) inhibitor (CHEBI:76779) |
| baicalein (CHEBI:2979) has role EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor (CHEBI:147285) |
| baicalein (CHEBI:2979) has role EC 4.1.1.17 (ornithine decarboxylase) inhibitor (CHEBI:139556) |
| baicalein (CHEBI:2979) has role ferroptosis inhibitor (CHEBI:173084) |
| baicalein (CHEBI:2979) has role geroprotector (CHEBI:176497) |
| baicalein (CHEBI:2979) has role hormone antagonist (CHEBI:49020) |
| baicalein (CHEBI:2979) has role plant metabolite (CHEBI:76924) |
| baicalein (CHEBI:2979) has role prostaglandin antagonist (CHEBI:49023) |
| baicalein (CHEBI:2979) has role radical scavenger (CHEBI:48578) |
| baicalein (CHEBI:2979) is a trihydroxyflavone (CHEBI:27116) |
| baicalein (CHEBI:2979) is conjugate acid of baicalein(1−) (CHEBI:78324) |
| Incoming Relation(s) |
| 5,6,7-trimethoxyflavone (CHEBI:2980) has functional parent baicalein (CHEBI:2979) |
| baicalin (CHEBI:2981) has functional parent baicalein (CHEBI:2979) |
| baicalein(1−) (CHEBI:78324) is conjugate base of baicalein (CHEBI:2979) |
| IUPAC Name |
|---|
| 5,6,7-trihydroxy-2-phenyl-4H-chromen-4-one |
| Synonyms | Source |
|---|---|
| 5,6,7-trihydroxy-2-phenyl-4H-1-benzopyran-4-one | IUPAC |
| 5,6,7-Trihydroxyflavone | KEGG COMPOUND |
| Baicalein | KEGG COMPOUND |
| NSC-661431 | ChEMBL |
| Brand Name | Source |
|---|---|
| Noroxylin | ChemIDplus |
| Manual Xrefs | Databases |
|---|---|
| 3WL | PDBeChem |
| 4444924 | ChemSpider |
| Baicalein | Wikipedia |
| C00001022 | KNApSAcK |
| C10023 | KEGG COMPOUND |
| CN102429899 | Patent |
| CPD-12724 | MetaCyc |
| DB16101 | DrugBank |
| FDB012057 | FooDB |
| HMDB0134890 | HMDB |
| LMPK12111095 | LIPID MAPS |
| LSM-6355 | LINCS |
| Registry Numbers | Sources |
|---|---|
| Reaxys:272683 | Reaxys |
| CAS:491-67-8 | KEGG COMPOUND |
| CAS:491-67-8 | ChemIDplus |
| Citations |
|---|