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CHEBI:27491 - leukotriene F4

ChEBI IDCHEBI:27491
ChEBI Nameleukotriene F4
Stars
ASCII Nameleukotriene F4
DefinitionA leukotriene composed of (7E,9E,11Z,14Z)-icosa-7,9,11,14-tetraenoic acid having (5S)-hydroxy and (6R)-(L-γ-glutamyl-L-cystein-S-yl) substituents.
Secondary ChEBI IDsCHEBI:6425, CHEBI:25028
Last Modified21 February 2017
DownloadsMolfile
FormulaC28H44N2O8S
Net Charge0
Average Mass568.733
Monoisotopic Mass568.28184
SMILESCCCCC/C=C\C/C=C\C=C\C=C\[C@@H](SC[C@H](NC(=O)CC[C@H](N)C(=O)O)C(=O)O)[C@@H](O)CCCC(=O)O
InChIInChI=1S/C28H44N2O8S/c1-2-3-4-5-6-7-8-9-10-11-12-13-16-24(23(31)15-14-17-26(33)34)39-20-22(28(37)38)30-25(32)19-18-21(29)27(35)36/h6-7,9-13,16,21-24,31H,2-5,8,14-15,17-20,29H2,1H3,(H,30,32)(H,33,34)(H,35,36)(H,37,38)/b7-6-,10-9-,12-11+,16-13+/t21-,22-,23-,24+/m0/s1
InChIKeyPYSODLWHFWCFLV-VJBFNVCUSA-N
Species of MetaboliteComponentSourceComments
Homo sapiens (ncbitaxon:9606) - DOI (10.1038/nbt.2488)
Roles Classification
Chemical Role:
Bronsted base  A molecular entity capable of accepting a hydron from a donor (Brønsted acid).
Biological Role:
human metabolite  Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens).
ChEBI Ontology
Outgoing Relation(s)
leukotriene F4 (CHEBI:27491) has functional parent icosa-7,9,11,14-tetraenoic acid (CHEBI:36038)
leukotriene F4 (CHEBI:27491) has role human metabolite (CHEBI:77746)
leukotriene F4 (CHEBI:27491) is a dipeptide (CHEBI:46761)
leukotriene F4 (CHEBI:27491) is a leukotriene (CHEBI:25029)
leukotriene F4 (CHEBI:27491) is a organic sulfide (CHEBI:16385)
leukotriene F4 (CHEBI:27491) is conjugate acid of leukotriene F4(2−) (CHEBI:133618)
Incoming Relation(s)
leukotriene F4(2−) (CHEBI:133618) is conjugate base of leukotriene F4 (CHEBI:27491)
IUPAC Name 
L-γ-glutamyl-S-[(4S,5R,6E,8E,10Z,13Z)-1-carboxy-4-hydroxynonadeca-6,8,10,13-tetraen-5-yl]-L-cysteine
Synonyms  Source
Leukotriene F4KEGG COMPOUND
LTF4KEGG COMPOUND
L-γ-glutamyl-S-{(1R,2E,4E,6Z,9Z)-1-[(1S)-4-carboxy-1-hydroxybutyl]pentadeca-2,4,6,9-tetraen-1-yl}-L-cysteineIUPAC
Leukotriene F-4ChemIDplus
5(S)-Hydroxy-6(R)-S-gamma-glutamylcysteine-7,9-trans-11,14-cis-eicosatetraenoic acidChemIDplus
Manual XrefsDatabases
C06462KEGG COMPOUND
LMFA03020009LIPID MAPS
HMDB0006465HMDB
US2002052001Patent
Registry NumbersSources
Reaxys:5676121Reaxys
CAS:83851-42-7ChemIDplus
Citations