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CHEBI:28787 - nitroglycerin
| Formula | C3H5N3O9 |
| Net Charge | 0 |
| Average Mass | 227.085 |
| Monoisotopic Mass | 227.00258 |
| SMILES | O=[N+]([O-])OCC(CO[N+](=O)[O-])O[N+](=O)[O-] |
| InChI | InChI=1S/C3H5N3O9/c7-4(8)13-1-3(15-6(11)12)2-14-5(9)10/h3H,1-2H2 |
| InChIKey | SNIOPGDIGTZGOP-UHFFFAOYSA-N |
| Wikipedia |
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| Roles Classification |
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| Chemical Roles: | explosive A substance capable of undergoing rapid and highly exothermic decomposition. nitric oxide donor An agent, with unique chemical structure and biochemical requirements, which generates nitric oxide. |
| Biological Roles: | xenobiotic A xenobiotic (Greek, xenos "foreign"; bios "life") is a compound that is foreign to a living organism. Principal xenobiotics include: drugs, carcinogens and various compounds that have been introduced into the environment by artificial means. analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. |
| Applications: | antirheumatic drug A drug used to treat rheumatoid arthritis. antiinfective agent A substance used in the prophylaxis or therapy of infectious diseases. muscle relaxant A drug used to produce muscle relaxation (excepting neuromuscular blocking agents). Its primary clinical and therapeutic use is the treatment of muscle spasm and immobility associated with strains, sprains, and injuries of the back and, to a lesser degree, injuries to the neck. Also used for the treatment of a variety of clinical conditions that have in common only the presence of skeletal muscle hyperactivity, for example, the muscle spasms that can occur in multiple sclerosis. antihypertensive agent Any drug used in the treatment of acute or chronic vascular hypertension regardless of pharmacological mechanism. vulnerary A drug used in treating and healing of wounds. anti-inflammatory agent Any compound that has anti-inflammatory effects. vasodilator agent A drug used to cause dilation of the blood vessels. prodrug A compound that, on administration, must undergo chemical conversion by metabolic processes before becoming the pharmacologically active drug for which it is a prodrug. cardiovascular drug A drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume. analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. tocolytic agent Any compound used to suppress premature labour and immature birth by suppressing uterine contractions. bone density conservation agent An agent that inhibits bone resorption and/or favor bone mineralization and bone regeneration. Used to heal bone fractures and to treat bone diseases such as osteopenia and osteoporosis. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| nitroglycerin (CHEBI:28787) has role analgesic (CHEBI:35480) |
| nitroglycerin (CHEBI:28787) has role anti-inflammatory agent (CHEBI:67079) |
| nitroglycerin (CHEBI:28787) has role antihypertensive agent (CHEBI:35674) |
| nitroglycerin (CHEBI:28787) has role antiinfective agent (CHEBI:35441) |
| nitroglycerin (CHEBI:28787) has role antineoplastic agent (CHEBI:35610) |
| nitroglycerin (CHEBI:28787) has role antirheumatic drug (CHEBI:35842) |
| nitroglycerin (CHEBI:28787) has role bone density conservation agent (CHEBI:50646) |
| nitroglycerin (CHEBI:28787) has role cardiovascular drug (CHEBI:35554) |
| nitroglycerin (CHEBI:28787) has role explosive (CHEBI:63490) |
| nitroglycerin (CHEBI:28787) has role muscle relaxant (CHEBI:51371) |
| nitroglycerin (CHEBI:28787) has role nitric oxide donor (CHEBI:50566) |
| nitroglycerin (CHEBI:28787) has role prodrug (CHEBI:50266) |
| nitroglycerin (CHEBI:28787) has role tocolytic agent (CHEBI:66993) |
| nitroglycerin (CHEBI:28787) has role vasodilator agent (CHEBI:35620) |
| nitroglycerin (CHEBI:28787) has role vulnerary (CHEBI:73336) |
| nitroglycerin (CHEBI:28787) has role xenobiotic (CHEBI:35703) |
| nitroglycerin (CHEBI:28787) is a nitroglycerol (CHEBI:25560) |
| IUPAC Name |
|---|
| 1,2,3-trinitrooxypropane |
| Synonyms | Source |
|---|---|
| 1,2,3-propanetrioltrinitrate | UM-BBD |
| 1,2,3-propanetriyl nitrate | NIST Chemistry WebBook |
| C01DA02 | ChEMBL |
| Chlormethine oxide hydrochloride | ChEMBL |
| Diluted nitroglycerin | ChEMBL |
| Glonoinum | ChEMBL |
| Brand Names | Source |
|---|---|
| Coro-nitro | ChEMBL |
| Deponit 10 | ChEMBL |
| Deponit 5 | ChEMBL |
| Glytrin | ChEMBL |
| Gonitro | ChEMBL |
| Lenitral 7.5 | ChEMBL |
| UniProt Name | Source |
|---|---|
| nitroglycerin | UniProt |
| Manual Xrefs | Databases |
|---|---|
| 1952 | DrugCentral |
| c0061 | UM-BBD |
| C07455 | KEGG COMPOUND |
| C07455 | KEGG COMPOUND |
| D00515 | KEGG DRUG |
| DB00727 | DrugBank |
| Glyceryl_trinitrate_(pharmacology) | Wikipedia |
| Nitroglycerin | Wikipedia |
| Citations |
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