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CHEBI:253342 - alosetron
| Formula | C17H18N4O |
| Net Charge | 0 |
| Average Mass | 294.358 |
| Monoisotopic Mass | 294.14806 |
| SMILES | Cc1ncnc1CN1CCc2c(c3ccccc3n2C)C1=O |
| InChI | InChI=1S/C17H18N4O/c1-11-13(19-10-18-11)9-21-8-7-15-16(17(21)22)12-5-3-4-6-14(12)20(15)2/h3-6,10H,7-9H2,1-2H3,(H,18,19) |
| InChIKey | JSWZEAMFRNKZNL-UHFFFAOYSA-N |
| Wikipedia |
|---|
| Roles Classification |
|---|
| Biological Role: | serotonergic antagonist Drugs that bind to but do not activate serotonin receptors, thereby blocking the actions of serotonin or serotonergic agonists. |
| Applications: | serotonergic antagonist Drugs that bind to but do not activate serotonin receptors, thereby blocking the actions of serotonin or serotonergic agonists. antiemetic A drug used to prevent nausea or vomiting. An antiemetic may act by a wide range of mechanisms: it might affect the medullary control centres (the vomiting centre and the chemoreceptive trigger zone) or affect the peripheral receptors. gastrointestinal drug A drug used for its effects on the gastrointestinal system, e.g. controlling gastric acidity, regulating gastrointestinal motility and water flow, and improving digestion. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| alosetron (CHEBI:253342) has role antiemetic (CHEBI:50919) |
| alosetron (CHEBI:253342) has role gastrointestinal drug (CHEBI:55324) |
| alosetron (CHEBI:253342) has role serotonergic antagonist (CHEBI:48279) |
| alosetron (CHEBI:253342) is a imidazoles (CHEBI:24780) |
| alosetron (CHEBI:253342) is a pyridoindole (CHEBI:48888) |
| Incoming Relation(s) |
| alosetron hydrochloride (CHEBI:53783) has part alosetron (CHEBI:253342) |
| IUPAC Name |
|---|
| 5-methyl-2-[(5-methyl-1H-imidazol-4-yl)methyl]-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indol-1-one |
| INN | Source |
|---|---|
| alosetron | KEGG DRUG |
| Synonym | Source |
|---|---|
| 2,3,4,5-Tetrahydro-5-methyl-2-((5-methyl-1H-imidazol-4-yl)methyl)-1H-pyrido(4,3-b)indol-1-one | ChemIDplus |