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CHEBI:234280 - Hexa-His

ChEBI IDCHEBI:234280
ChEBI NameHexa-His
Stars
DefinitionA hexapeptide formed from six L-histidine residues joined in sequence by peptide linkages. It is an affinity tag used for protein purification.
Last Modified15 May 2025
SubmitterAdnan
DownloadsMolfile
FormulaC36H44N18O7
Net Charge0
Average Mass840.867
Monoisotopic Mass840.36404
SMILESN[C@@H](Cc1cncn1)C(=O)N[C@@H](Cc1cncn1)C(=O)N[C@@H](Cc1cncn1)C(=O)N[C@@H](Cc1cncn1)C(=O)N[C@@H](Cc1cncn1)C(=O)N[C@@H](Cc1cncn1)C(=O)O
InChIInChI=1S/C36H44N18O7/c37-25(1-19-7-38-13-44-19)31(55)50-26(2-20-8-39-14-45-20)32(56)51-27(3-21-9-40-15-46-21)33(57)52-28(4-22-10-41-16-47-22)34(58)53-29(5-23-11-42-17-48-23)35(59)54-30(36(60)61)6-24-12-43-18-49-24/h7-18,25-30H,1-6,37H2,(H,38,44)(H,39,45)(H,40,46)(H,41,47)(H,42,48)(H,43,49)(H,50,55)(H,51,56)(H,52,57)(H,53,58)(H,54,59)(H,60,61)/t25-,26-,27-,28-,29-,30-/m0/s1
InChIKeyXSYUPRQVAHJETO-WPMUBMLPSA-N
Roles Classification
Chemical Role:
Bronsted base  A molecular entity capable of accepting a hydron from a donor (Brønsted acid).
ChEBI Ontology
Outgoing Relation(s)
Hexa-His (CHEBI:234280) has functional parent L-histidine (CHEBI:15971)
Hexa-His (CHEBI:234280) is a hexapeptide (CHEBI:233722)
IUPAC Name 
L-histidyl-L-histidyl-L-histidyl-L-histidyl-L-histidyl-L-histidine
Synonyms  Source
L-His-L-His-L-His-L-His-L-His-L-HisChEBI
6XHis tagChEBI
6X His tagChEBI
L-histidine hexapeptideChEBI
L-His-L-His-L-His-L-His-L-His-L-His-OHChEBI
hexa histidine-tagChEBI
Registry NumbersSources
CAS:64134-30-1PubChem Compound
Citations