EMBL-EBI | Chemical Biology | ChEBI
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| ChEBI ID | CHEBI:230518 |
| ChEBI Name | Defencath |
| Stars | |
| Definition | A mixture containing taurolidine (a thiadiazinane antimicrobial) and heparin sodium (an anti-coagulant). It is used to reduce the incidence of catheter-related bloodstream infections in adult patients with kidney failure receiving chronic hemodialysis through a central venous catheter. |
| Last Modified | 19 April 2024 |
| Submitter | Adnan |
| Wikipedia |
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| Roles Classification |
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| Biological Role: | antimicrobial agent A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans. |
| Applications: | antiinfective agent A substance used in the prophylaxis or therapy of infectious diseases. antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. anticoagulant An agent that prevents blood clotting. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| Defencath (CHEBI:230518) has part heparin sodium (CHEBI:230519) |
| Defencath (CHEBI:230518) has part taurolidine (CHEBI:135173) |
| Defencath (CHEBI:230518) has role anticoagulant (CHEBI:50249) |
| Defencath (CHEBI:230518) has role antiinfective agent (CHEBI:35441) |
| Defencath (CHEBI:230518) has role antimicrobial agent (CHEBI:33281) |
| Defencath (CHEBI:230518) has role antineoplastic agent (CHEBI:35610) |
| Defencath (CHEBI:230518) is a mixture (CHEBI:60004) |
| Synonyms | Source |
|---|---|
| taurolidine/heparin | ChEBI |
| taurolidine and heparin | KEGG DRUG |
| taurolidine, heparin | ChEBI |
| Brand Name | Source |
|---|---|
| Defencath | KEGG DRUG |
| Manual Xrefs | Databases |
|---|---|
| Taurolidine/heparin | Wikipedia |
| D12737 | KEGG DRUG |
| Citations |
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