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CHEBI:135173 - taurolidine

Default Structure
ChEBI IDCHEBI:135173
ChEBI Nametaurolidine
Stars
DefinitionA member of the class of thiadiazinanes that is 1,2,4-thiadiazinane 1,1-dioxide substituted by a (1,1-dioxido-1,2,4-thiadiazinan-4-yl)methyl group at position 4. It is a broad-spectrum antiseptic used as lock therapy solution in patients with long term central venous catheters for the prevention of catheter related bloodstream infections.
Last Modified19 April 2024
DownloadsMolfile
FormulaC7H16N4O4S2
Net Charge0
Average Mass284.363
Monoisotopic Mass284.06130
SMILESO=S1(=O)CCN(CN2CCS(=O)(=O)NC2)CN1
InChIInChI=1S/C7H16N4O4S2/c12-16(13)3-1-10(5-8-16)7-11-2-4-17(14,15)9-6-11/h8-9H,1-7H2
InChIKeyAJKIRUJIDFJUKJ-UHFFFAOYSA-N
Wikipedia
Roles Classification
Biological Roles:
antifungal agent  An antimicrobial agent that destroys fungi by suppressing their ability to grow or reproduce.
antibacterial agent  A substance (or active part thereof) that kills or slows the growth of bacteria.
Applications:
anti-inflammatory agent  Any compound that has anti-inflammatory effects.
antineoplastic agent  A substance that inhibits or prevents the proliferation of neoplasms.
antiseptic drug  A substance used locally on humans and other animals to destroy harmful microorganisms or to inhibit their activity (cf. disinfectants, which destroy microorganisms found on non-living objects, and antibiotics, which can be transported through the lymphatic system to destroy bacteria within the body).
ChEBI Ontology
Outgoing Relation(s)
taurolidine (CHEBI:135173) has role anti-inflammatory agent (CHEBI:67079)
taurolidine (CHEBI:135173) has role antibacterial agent (CHEBI:33282)
taurolidine (CHEBI:135173) has role antifungal agent (CHEBI:35718)
taurolidine (CHEBI:135173) has role antineoplastic agent (CHEBI:35610)
taurolidine (CHEBI:135173) has role antiseptic drug (CHEBI:48218)
taurolidine (CHEBI:135173) is a sulfone (CHEBI:35850)
taurolidine (CHEBI:135173) is a thiadiazinane (CHEBI:38781)
Incoming Relation(s)
Defencath (CHEBI:230518) has part taurolidine (CHEBI:135173)
IUPAC Name 
4,4'-methanediylbis(1,2,4-thiadiazinane) 1,1,1',1'-tetraoxide
INNs  Source
taurolidinaWHO MedNet
taurolidineWHO MedNet
taurolidineWHO MedNet
taurolidinumWHO MedNet
Synonyms  Source
4,4'-methylenebis(1,2,4-thiadiazinane)-1,1,1',1'-tetraoxideChEBI
4,4'-methylenebis(perhydro-1,2,4-thiadiazin 1,1-dioxide)ChEBI
4,4'-methylenedi(1λ6,2,4-thiadiazinane-1,1-dione)IUPAC
taurolinDrugCentral
taurolineDrugCentral
W-3100MDrugBank
Manual XrefsDatabases
2568DrugCentral
D07146KEGG DRUG
DB12473DrugBank
HMDB0258744HMDB
TaurolidineWikipedia
Registry NumbersSources
CAS:19388-87-5KEGG DRUG
Citations