5-azacytidine (CHEBI:2038)

CHEBI:2038 - 5-azacytidine

ChEBI ID	CHEBI:2038
ChEBI Name	5-azacytidine
Stars
Definition	An N-glycosyl-1,3,5-triazine that is 4-amino-1,3,5-triazin-2(1H)-one substituted by a β-D-ribofuranosyl residue via an N-glycosidic linkage. An antineoplastic agent, it is used in the treatment of myeloid leukaemia.
Last Modified	19 June 2018
Downloads	Molfile

Formula	C8H12N4O5
Net Charge	0
Average Mass	244.207
Monoisotopic Mass	244.08077
SMILES	Nc1ncn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
InChI	InChI=1S/C8H12N4O5/c9-7-10-2-12(8(16)11-7)6-5(15)4(14)3(1-13)17-6/h2-6,13-15H,1H2,(H2,9,11,16)/t3-,4-,5-,6-/m1/s1
InChIKey	NMUSYJAQQFHJEW-KVTDHHQDSA-N

Wikipedia

Roles Classification

antitubercular agent A substance that kills or slows the growth of Mycobacterium tuberculosis and is used in the treatment of tuberculosis.

renoprotective agent Any compound that is able to prevent damage to the kidneys.

antifibrotic agent Any agent which acts to reduce fibrosis.

anti-anaemic agent A compound which increases either the number of red cells or the amount of haemoglobin in the blood.

antitubercular agent A substance that kills or slows the growth of Mycobacterium tuberculosis and is used in the treatment of tuberculosis.

antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms.

ChEBI Ontology

Outgoing Relation(s)
	5-azacytidine (CHEBI:2038) has functional parent β-D-ribose (CHEBI:47002)
	5-azacytidine (CHEBI:2038) has role anti-anaemic agent (CHEBI:75835)
	5-azacytidine (CHEBI:2038) has role antifibrotic agent (CHEBI:233423)
	5-azacytidine (CHEBI:2038) has role antineoplastic agent (CHEBI:35610)
	5-azacytidine (CHEBI:2038) has role antitubercular agent (CHEBI:33231)
	5-azacytidine (CHEBI:2038) has role renoprotective agent (CHEBI:231911)
	5-azacytidine (CHEBI:2038) is a N-glycosyl-1,3,5-triazine (CHEBI:48009)
	5-azacytidine (CHEBI:2038) is a nucleoside analogue (CHEBI:60783)

IUPAC Names
4-amino-1-β-D-ribofuranosyl-1,3,5-triazin-2(1H)-one
5-azacytidine

INNs	Source
azacitidina	ChemIDplus
azacitidinum	ChemIDplus

Synonyms	Source
4-Amino-1-beta-D-ribofuranosyl-s-triazin-2(1H)-one	ChemIDplus
5-azacitidine	ChEMBL
5-Azacytidine	KEGG COMPOUND
azacitidine	ChEMBL
Azacitidine	KEGG COMPOUND
NSC-102816	ChEMBL

Citations