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CHEBI:194100 - Ru360

Default Structure
ChEBI IDCHEBI:194100
ChEBI NameRu360
Stars
DefinitionA binuclear oxo-bridged Ru compound that selectively inhibits mitochondrial calcium uniporter mediated Ca2+-uptake with nanomolar potency in cells.
Last Modified23 December 2022
SubmitterTheOtherDave
DownloadsMolfile
FormulaC2H26N8O5Ru2.3Cl
Net Charge+5
Average Mass550.780
Monoisotopic Mass550.91513
SMILES[Cl-].[Cl-].[Cl-].[H]C(=O)[O][Ru]([NH3+])([NH3+])([NH3+])([NH3+])[O][Ru]([NH3+])([NH3+])([NH3+])([NH3+])[O]C([H])=O
InChIInChI=1S/2CH2O2.3ClH.8H3N.O.2Ru/c2*2-1-3;;;;;;;;;;;;;;/h2*1H,(H,2,3);3*1H;8*1H3;;;/q;;;;;;;;;;;;;;2*+5/p-5
InChIKeyGAQYLINTMDTWDS-UHFFFAOYSA-I
Wikipedia
Roles Classification
Biological Roles:
calcium channel blocker  One of a class of drugs that acts by selective inhibition of calcium influx through cell membranes or on the release and binding of calcium in intracellular pools.
mitochondrial calcium uniporter inhibitor  Any inhibitor of mitochondrial calcium uniporter.
Application:
cardioprotective agent  Any protective agent that is able to prevent damage to the heart.
ChEBI Ontology
Outgoing Relation(s)
Ru360 (CHEBI:194100) has role calcium channel blocker (CHEBI:38215)
Ru360 (CHEBI:194100) has role cardioprotective agent (CHEBI:77307)
Ru360 (CHEBI:194100) has role mitochondrial calcium uniporter inhibitor (CHEBI:194181)
Ru360 (CHEBI:194100) is a ruthenium coordination entity (CHEBI:35733)
Synonyms  Source
Ru 360ChEBI
Ru-360ChEBI
Ru360ChEBI
ruthenium 360SUBMITTER
ruthenium-360ChEBI
Manual XrefsDatabases
Ru360Wikipedia
Registry NumbersSources
CAS:133399-54-9ChEBI
Citations