EMBL-EBI | Chemical Biology | ChEBI
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| ChEBI ID | CHEBI:192712 |
| ChEBI Name | Paxlovid |
| Stars | |
| Definition | A mixture containing nirmatrelvir and ritonavir. It is co-administered in tablet form for the treatment and post-exposure prophylaxis of COVID-19. |
| Last Modified | 15 July 2022 |
| Submitter | Adnan |
| Wikipedia |
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| Roles Classification |
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| Biological Roles: | EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor An EC 3.4.22.* (cysteine endopeptidase) inhibitor that interferes with the action of SARS coronavirus main proteinase (EC 3.4.22.69). HIV protease inhibitor An inhibitor of HIV protease, an enzyme required for production of proteins needed for viral assembly. anticoronaviral agent Any antiviral agent which inhibits the activity of coronaviruses. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| Paxlovid (CHEBI:192712) has part nirmatrelvir (CHEBI:170007) |
| Paxlovid (CHEBI:192712) has part ritonavir (CHEBI:45409) |
| Paxlovid (CHEBI:192712) has role anticoronaviral agent (CHEBI:149553) |
| Paxlovid (CHEBI:192712) has role EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor (CHEBI:147285) |
| Paxlovid (CHEBI:192712) has role HIV protease inhibitor (CHEBI:35660) |
| Paxlovid (CHEBI:192712) is a mixture (CHEBI:60004) |
| Synonyms | Source |
|---|---|
| PF-07321332 and ritonavir drug combination | ChEBI |
| nirmatrelvir mixture with ritonavir | ChEBI |
| nirmatrelvir and ritonavir | KEGG DRUG |
| PF-07321332, ritonavir | ChEBI |
| nirmatrelvir/ritonavir | ChEBI |
| nirmatrelvir, ritonavir | ChEBI |
| Brand Name | Source |
|---|---|
| Paxlovid | KEGG DRUG |
| Manual Xrefs | Databases |
|---|---|
| Nirmatrelvir/ritonavir | Wikipedia |
| D12269 | KEGG DRUG |
| Citations |
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