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CHEBI:191178 - goralatide

Default Structure
ChEBI IDCHEBI:191178
ChEBI Namegoralatide
Stars
DefinitionA tetrapeptide that is Ser-Asp-Lys-Pro in which the N-terminal amino group carries an acetyl group. It is selective inhibitor of primitive haematopoietic cell proliferation and exhibits anti-inflammatory, anti-fibrotic, and pro-angiogenic properties.
Secondary ChEBI IDCHEBI:168934
Last Modified5 June 2025
SubmitterAdnan, MetaboLights
DownloadsMolfile
FormulaC20H33N5O9
Net Charge0
Average Mass487.510
Monoisotopic Mass487.22783
SMILESCC(=O)N[C@@H](CO)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)O
InChIInChI=1S/C20H33N5O9/c1-11(27)22-14(10-26)18(31)24-13(9-16(28)29)17(30)23-12(5-2-3-7-21)19(32)25-8-4-6-15(25)20(33)34/h12-15,26H,2-10,21H2,1H3,(H,22,27)(H,23,30)(H,24,31)(H,28,29)(H,33,34)/t12-,13-,14-,15-/m0/s1
InChIKeyHJDRXEQUFWLOGJ-AJNGGQMLSA-N
Species of MetaboliteComponentSourceComments
Malus domestica (ncbitaxon:3750) exocarp (BTO:0000733) MetaboLights (MTBLS2384) Strain: Malus x domestica Borkh. cv. Ruixue
Roles Classification
Chemical Role:
Bronsted base  A molecular entity capable of accepting a hydron from a donor (Brønsted acid).
Applications:
pro-angiogenic agent  Any compound that promotes the growth of new blood vessels from pre-existing vessels.
anti-inflammatory agent  Any compound that has anti-inflammatory effects.
ChEBI Ontology
Outgoing Relation(s)
goralatide (CHEBI:191178) has functional parent Ser-Asp-Lys-Pro (CHEBI:191177)
goralatide (CHEBI:191178) has role anti-inflammatory agent (CHEBI:67079)
goralatide (CHEBI:191178) has role pro-angiogenic agent (CHEBI:72571)
goralatide (CHEBI:191178) is a tetrapeptide (CHEBI:48030)
goralatide (CHEBI:191178) is conjugate acid of goralatide(1−) (CHEBI:190701)
Incoming Relation(s)
goralatide(1−) (CHEBI:190701) is conjugate base of goralatide (CHEBI:191178)
IUPAC Name 
N-acetyl-L-seryl-L-α-aspartyl-L-lysyl-L-proline
INNs  Source
goralatidaWHO MedNet
goralatideWHO MedNet
goralatideWHO MedNet
goralatidumWHO MedNet
Synonyms  Source
(2S)-1-[(2S)-2-{[(2S)-2-{[(2S)-2-acetamido-3-hydroxypropanoyl]amino}-3-carboxypropanoyl]amino}-6-aminohexanoyl]pyrrolidine-2-carboxylic acidIUPAC
acetyl-N-Ser-Asp-Lys-ProChEBI
acetyl-seryl-aspartyl-lysyl-prolineChEBI
Ac-SDKPHMDB
AcSDKPChEBI
Ac-Ser-Asp-Lys-ProChEBI
Manual XrefsDatabases
59343ChemSpider
HMDB0062552HMDB
Registry NumbersSources
CAS:120081-14-3ChemIDplus
Citations