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CHEBI:18723 - nicotine
| ChEBI ID | CHEBI:18723 |
| ChEBI Name | nicotine |
| Stars | |
| Definition | A racemate composed of equimolar amounts of (R)- and (S)-nicotine. |
| Last Modified | 26 July 2017 |
| Wikipedia |
|---|
| Species of Metabolite | Component | Source | Comments |
|---|---|---|---|
| Nicotiana tabacum (ncbitaxon:4097) | - | PubMed (11559179) |
| Roles Classification |
|---|
| Biological Roles: | teratogenic agent A role played by a chemical compound in biological systems with adverse consequences in embryo developments, leading to birth defects, embryo death or altered development, growth retardation and functional defect. immunomodulator Biologically active substance whose activity affects or plays a role in the functioning of the immune system. mitogen A chemical substance that encourages a cell to commence cell division, triggering mitosis. nicotinic acetylcholine receptor agonist An agonist that selectively binds to and activates a nicotinic acetylcholine receptor. neurotoxin A poison that interferes with the functions of the nervous system. |
| Applications: | immunomodulator Biologically active substance whose activity affects or plays a role in the functioning of the immune system. peripheral nervous system drug A drug that acts principally at one or more sites within the peripheral neuroeffector systems, the autonomic system, and motor nerve-skeletal system. anxiolytic drug Anxiolytic drugs are agents that alleviate anxiety, tension, and anxiety disorders, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions. psychotropic drug A loosely defined grouping of drugs that have effects on psychological function. nicotinic acetylcholine receptor agonist An agonist that selectively binds to and activates a nicotinic acetylcholine receptor. biomarker A substance used as an indicator of a biological state. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| nicotine (CHEBI:18723) has part (R)-nicotine (CHEBI:39162) |
| nicotine (CHEBI:18723) has part (S)-nicotine (CHEBI:17688) |
| nicotine (CHEBI:18723) has role anxiolytic drug (CHEBI:35474) |
| nicotine (CHEBI:18723) has role biomarker (CHEBI:59163) |
| nicotine (CHEBI:18723) has role immunomodulator (CHEBI:50846) |
| nicotine (CHEBI:18723) has role mitogen (CHEBI:52290) |
| nicotine (CHEBI:18723) has role neurotoxin (CHEBI:50910) |
| nicotine (CHEBI:18723) has role nicotinic acetylcholine receptor agonist (CHEBI:47958) |
| nicotine (CHEBI:18723) has role peripheral nervous system drug (CHEBI:49110) |
| nicotine (CHEBI:18723) has role psychotropic drug (CHEBI:35471) |
| nicotine (CHEBI:18723) has role teratogenic agent (CHEBI:50905) |
| nicotine (CHEBI:18723) is a racemate (CHEBI:60911) |
| Incoming Relation(s) |
| 6-hydroxynicotine (CHEBI:24729) has functional parent nicotine (CHEBI:18723) |
| cotinine N-oxide (CHEBI:89087) has functional parent nicotine (CHEBI:18723) |
| (S)-nornicotine (CHEBI:28313) has parent hydride nicotine (CHEBI:18723) |
| nicotine N1'-oxide (CHEBI:30734) has parent hydride nicotine (CHEBI:18723) |
| IUPAC Name |
|---|
| rac-3-(1-methylpyrrolidin-2-yl)pyridine |
| Synonyms | Source |
|---|---|
| (+-)-3-(1-Methyl-2-pyrrolidinyl)pyridine | KEGG COMPOUND |
| (R,S)-nicotine | ChemIDplus |
| (RS)-nicotine | UM-BBD |
| nicotin | ChEBI |
| (±)-nicotine | ChemIDplus |
| nikotin | ChEBI |
| Registry Numbers | Sources |
|---|---|
| Reaxys:82108 | Reaxys |
| Beilstein:82111 | Beilstein |
| CAS:22083-74-5 | KEGG COMPOUND |
| CAS:22083-74-5 | ChemIDplus |
| Citations |
|---|