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CHEBI:18723 - nicotine
| ChEBI ID | CHEBI:18723 |
| ChEBI Name | nicotine |
| Stars | |
| Definition | A racemate composed of equimolar amounts of (R)- and (S)-nicotine. |
| Last Modified | 26 July 2017 |
| Wikipedia |
|---|
| Species of Metabolite | Component | Source | Comments |
|---|---|---|---|
| Nicotiana tabacum (ncbitaxon:4097) | - | PubMed (11559179) |
| Roles Classification |
|---|
| Biological Roles: | nicotinic acetylcholine receptor agonist An agonist that selectively binds to and activates a nicotinic acetylcholine receptor. neurotoxin A poison that interferes with the functions of the nervous system. teratogenic agent A role played by a chemical compound in biological systems with adverse consequences in embryo developments, leading to birth defects, embryo death or altered development, growth retardation and functional defect. mitogen A chemical substance that encourages a cell to commence cell division, triggering mitosis. immunomodulator Biologically active substance whose activity affects or plays a role in the functioning of the immune system. |
| Applications: | nicotinic acetylcholine receptor agonist An agonist that selectively binds to and activates a nicotinic acetylcholine receptor. psychotropic drug A loosely defined grouping of drugs that have effects on psychological function. peripheral nervous system drug A drug that acts principally at one or more sites within the peripheral neuroeffector systems, the autonomic system, and motor nerve-skeletal system. biomarker A substance used as an indicator of a biological state. anxiolytic drug Anxiolytic drugs are agents that alleviate anxiety, tension, and anxiety disorders, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions. immunomodulator Biologically active substance whose activity affects or plays a role in the functioning of the immune system. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| nicotine (CHEBI:18723) has part (R)-nicotine (CHEBI:39162) |
| nicotine (CHEBI:18723) has part (S)-nicotine (CHEBI:17688) |
| nicotine (CHEBI:18723) has role anxiolytic drug (CHEBI:35474) |
| nicotine (CHEBI:18723) has role biomarker (CHEBI:59163) |
| nicotine (CHEBI:18723) has role immunomodulator (CHEBI:50846) |
| nicotine (CHEBI:18723) has role mitogen (CHEBI:52290) |
| nicotine (CHEBI:18723) has role neurotoxin (CHEBI:50910) |
| nicotine (CHEBI:18723) has role nicotinic acetylcholine receptor agonist (CHEBI:47958) |
| nicotine (CHEBI:18723) has role peripheral nervous system drug (CHEBI:49110) |
| nicotine (CHEBI:18723) has role psychotropic drug (CHEBI:35471) |
| nicotine (CHEBI:18723) has role teratogenic agent (CHEBI:50905) |
| nicotine (CHEBI:18723) is a racemate (CHEBI:60911) |
| Incoming Relation(s) |
| 6-hydroxynicotine (CHEBI:24729) has functional parent nicotine (CHEBI:18723) |
| cotinine N-oxide (CHEBI:89087) has functional parent nicotine (CHEBI:18723) |
| (S)-nornicotine (CHEBI:28313) has parent hydride nicotine (CHEBI:18723) |
| nicotine N1'-oxide (CHEBI:30734) has parent hydride nicotine (CHEBI:18723) |
| IUPAC Name |
|---|
| rac-3-(1-methylpyrrolidin-2-yl)pyridine |
| Synonyms | Source |
|---|---|
| (+-)-3-(1-Methyl-2-pyrrolidinyl)pyridine | KEGG COMPOUND |
| (R,S)-nicotine | ChemIDplus |
| (RS)-nicotine | UM-BBD |
| nicotin | ChEBI |
| (±)-nicotine | ChemIDplus |
| nikotin | ChEBI |
| Registry Numbers | Sources |
|---|---|
| Reaxys:82108 | Reaxys |
| Beilstein:82111 | Beilstein |
| CAS:22083-74-5 | KEGG COMPOUND |
| CAS:22083-74-5 | ChemIDplus |
| Citations |
|---|