(6S)-5-methyltetrahydrofolate(2-) (CHEBI:18608)

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CHEBI:18608 - (6S)-5-methyltetrahydrofolate(2−)

ChEBI ID	CHEBI:18608
ChEBI Name	(6S)-5-methyltetrahydrofolate(2−)
Stars
ASCII Name	(6S)-5-methyltetrahydrofolate(2-)
Last Modified	14 February 2022
Downloads	Molfile

Formula	C20H23N7O6
Net Charge	-2
Average Mass	457.447
Monoisotopic Mass	457.17208
SMILES	CN1c2c(nc(N)nc2=O)NC[C@@H]1CNc1ccc(C(=O)N[C@@H](CCC(=O)[O-])C(=O)[O-])cc1
InChI	InChI=1S/C20H25N7O6/c1-27-12(9-23-16-15(27)18(31)26-20(21)25-16)8-22-11-4-2-10(3-5-11)17(30)24-13(19(32)33)6-7-14(28)29/h2-5,12-13,22H,6-9H2,1H3,(H,24,30)(H,28,29)(H,32,33)(H4,21,23,25,26,31)/p-2/t12-,13-/m0/s1
InChIKey	ZNOVTXRBGFNYRX-STQMWFEESA-L

Species of Metabolite	Component	Source	Comments
Homo sapiens (ncbitaxon:9606)	-	DOI (10.1038/nbt.2488)
Saccharomyces cerevisiae (ncbitaxon:4932)	-	PubMed (24678285)	Source: yeast.sf.net

Roles Classification

Biological Roles:

human metabolite Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens).

Saccharomyces cerevisiae metabolite Any fungal metabolite produced during a metabolic reaction in Baker's yeast (Saccharomyces cerevisiae ).

water-soluble vitamin (role) Any vitamin that dissolves in water and readily absorbed into tissues for immediate use. Unlike the fat-soluble vitamins, they are not stored in the body and need to be replenished regularly in the diet and will rarely accumulate to toxic levels since they are quickly excreted from the body via urine.

Application:

nutraceutical A product in capsule, tablet or liquid form that provide essential nutrients, such as a vitamin, an essential mineral, a protein, an herb, or similar nutritional substance.

ChEBI Ontology

Outgoing Relation(s)
	(6S)-5-methyltetrahydrofolate(2−) (CHEBI:18608) has role Saccharomyces cerevisiae metabolite (CHEBI:75772)
	(6S)-5-methyltetrahydrofolate(2−) (CHEBI:18608) has role human metabolite (CHEBI:77746)
	(6S)-5-methyltetrahydrofolate(2−) (CHEBI:18608) is a 5-methyltetrahydrofolate(2−) (CHEBI:189667)
	(6S)-5-methyltetrahydrofolate(2−) (CHEBI:18608) is conjugate base of (6S)-5-methyltetrahydrofolic acid (CHEBI:136009)
Incoming Relation(s)
	levomefolate calcium (CHEBI:189695) has part (6S)-5-methyltetrahydrofolate(2−) (CHEBI:18608)
	(6S)-5-methyltetrahydrofolic acid (CHEBI:136009) is conjugate acid of (6S)-5-methyltetrahydrofolate(2−) (CHEBI:18608)

IUPAC Name
(2S)-2-{[4-({[(6S)-2-amino-5-methyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]amino}pentanedioate

Synonym	Source
(6S)-5-methyltetrahydrofolate	ChEBI

UniProt Name	Source
(6S)-5-methyl-5,6,7,8-tetrahydrofolate	UniProt

Manual Xrefs	Databases
5-METHYL-THF	MetaCyc

Registry Numbers	Sources
Beilstein:10132446	Beilstein