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CHEBI:18145 - (R,R,R)-α-tocopherol
| Formula | C29H50O2 |
| Net Charge | 0 |
| Average Mass | 430.717 |
| Monoisotopic Mass | 430.38108 |
| SMILES | Cc1c(C)c2c(c(C)c1O)CC[C@@](C)(CCC[C@H](C)CCC[C@H](C)CCCC(C)C)O2 |
| InChI | InChI=1S/C29H50O2/c1-20(2)12-9-13-21(3)14-10-15-22(4)16-11-18-29(8)19-17-26-25(7)27(30)23(5)24(6)28(26)31-29/h20-22,30H,9-19H2,1-8H3/t21-,22-,29-/m1/s1 |
| InChIKey | GVJHHUAWPYXKBD-IEOSBIPESA-N |
| Wikipedia |
|---|
| Species of Metabolite | Component | Source | Comments |
|---|---|---|---|
| Chlamydomonas reinhardtii (ncbitaxon:3055) | - | PubMed (25515814) | |
| Homo sapiens (ncbitaxon:9606) | |||
| faeces (UBERON:0001988) | PubMed (24029555) | ||
| saliva (UBERON:0001836) | PubMed (17623524) | ||
| cerebrospinal fluid (UBERON:0001359) | PubMed (8857741) | ||
| blood (UBERON:0000178) | PubMed (7657478) | ||
| breast milk (ENVO:02000031) | PubMed (2388136) | ||
| - | DOI (10.1038/nbt.2488) | ||
| Mus musculus (ncbitaxon:10090) | - | MetaboLights (MTBLS345) | From MetaboLights |
| Roles Classification |
|---|
| Chemical Roles: | antioxidant A substance that opposes oxidation or inhibits reactions brought about by dioxygen or peroxides. food antioxidant An antioxidant that used as a food additives to help guard against food deterioration. antioxidant A substance that opposes oxidation or inhibits reactions brought about by dioxygen or peroxides. antioxidant A substance that opposes oxidation or inhibits reactions brought about by dioxygen or peroxides. antioxidant A substance that opposes oxidation or inhibits reactions brought about by dioxygen or peroxides. antioxidant A substance that opposes oxidation or inhibits reactions brought about by dioxygen or peroxides. |
| Biological Roles: | antiviral agent A substance that destroys or inhibits replication of viruses. algal metabolite Any eukaryotic metabolite produced during a metabolic reaction in algae including unicellular organisms like chlorella and diatoms to multicellular organisms like giant kelps and brown algae. EC 2.7.11.13 (protein kinase C) inhibitor An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of protein kinase C (EC 2.7.11.13). immunomodulator Biologically active substance whose activity affects or plays a role in the functioning of the immune system. plant metabolite Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms. micronutrient Any nutrient required in small quantities by organisms throughout their life in order to orchestrate a range of physiological functions. plant metabolite Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms. food antioxidant An antioxidant that used as a food additives to help guard against food deterioration. analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. fat-soluble vitamin (role) Any vitamin that dissolves in fats and are stored in body tissues. Unlike the water-soluble vitamins, they are stored in the body for long periods of time and generally pose a greater risk for toxicity when consumed in excess. analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. fat-soluble vitamin (role) Any vitamin that dissolves in fats and are stored in body tissues. Unlike the water-soluble vitamins, they are stored in the body for long periods of time and generally pose a greater risk for toxicity when consumed in excess. |
| Applications: | nutraceutical A product in capsule, tablet or liquid form that provide essential nutrients, such as a vitamin, an essential mineral, a protein, an herb, or similar nutritional substance. antiatherogenic agent A cardiovascular drug that prevents atherogenesis, the accumulation of lipid-containing plaques on the innermost layers of the arteries. Compare with antiatherosclerotic agent. anticoagulant An agent that prevents blood clotting. immunomodulator Biologically active substance whose activity affects or plays a role in the functioning of the immune system. food antioxidant An antioxidant that used as a food additives to help guard against food deterioration. analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. cardiovascular drug A drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume. antiparkinson drug A drug used in the treatment of Parkinson's disease. antiatherosclerotic agent A cardiovascular drug that prevents atherosclerosis (a disease in which the inside of an artery narrows due to the build up of plaque). Compare with antiatherogenic agent. antipsychotic agent Antipsychotic drugs are agents that control agitated psychotic behaviour, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect. hypoglycemic agent A drug which lowers the blood glucose level. anti-inflammatory agent Any compound that has anti-inflammatory effects. vulnerary A drug used in treating and healing of wounds. antidote Any protective agent counteracting or neutralizing the action of poisons. antifibrotic agent Any agent which acts to reduce fibrosis. renoprotective agent Any compound that is able to prevent damage to the kidneys. antiinfective agent A substance used in the prophylaxis or therapy of infectious diseases. anti-asthmatic agent Any compound that has anti-asthmatic effects. anti-anaemic agent A compound which increases either the number of red cells or the amount of haemoglobin in the blood. antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. antipsoriatic A drug used to treat psoriasis. hepatoprotective agent Any compound that is able to prevent damage to the liver. ophthalmology drug Any compound used for the treatment of eye conditions or eye diseases. antiglaucoma drug Any drug which can be used to prevent or alleviate glaucoma, a disease in which the optic nerve is damaged, resulting in progressive, irreversible loss of vision. It is often, though not always, associated with increased pressure of the fluid in the eye. antirheumatic drug A drug used to treat rheumatoid arthritis. antidepressant Antidepressants are mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. cardiovascular drug A drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume. antiparkinson drug A drug used in the treatment of Parkinson's disease. antiatherosclerotic agent A cardiovascular drug that prevents atherosclerosis (a disease in which the inside of an artery narrows due to the build up of plaque). Compare with antiatherogenic agent. antipsychotic agent Antipsychotic drugs are agents that control agitated psychotic behaviour, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect. hypoglycemic agent A drug which lowers the blood glucose level. anti-inflammatory agent Any compound that has anti-inflammatory effects. vulnerary A drug used in treating and healing of wounds. antidote Any protective agent counteracting or neutralizing the action of poisons. antifibrotic agent Any agent which acts to reduce fibrosis. renoprotective agent Any compound that is able to prevent damage to the kidneys. antiinfective agent A substance used in the prophylaxis or therapy of infectious diseases. anti-asthmatic agent Any compound that has anti-asthmatic effects. anti-anaemic agent A compound which increases either the number of red cells or the amount of haemoglobin in the blood. antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. antipsoriatic A drug used to treat psoriasis. hepatoprotective agent Any compound that is able to prevent damage to the liver. ophthalmology drug Any compound used for the treatment of eye conditions or eye diseases. antiglaucoma drug Any drug which can be used to prevent or alleviate glaucoma, a disease in which the optic nerve is damaged, resulting in progressive, irreversible loss of vision. It is often, though not always, associated with increased pressure of the fluid in the eye. antirheumatic drug A drug used to treat rheumatoid arthritis. antidepressant Antidepressants are mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| (R,R,R)-α-tocopherol (CHEBI:18145) has role algal metabolite (CHEBI:84735) |
| (R,R,R)-α-tocopherol (CHEBI:18145) has role antiatherogenic agent (CHEBI:50855) |
| (R,R,R)-α-tocopherol (CHEBI:18145) has role anticoagulant (CHEBI:50249) |
| (R,R,R)-α-tocopherol (CHEBI:18145) has role antioxidant (CHEBI:22586) |
| (R,R,R)-α-tocopherol (CHEBI:18145) has role antiviral agent (CHEBI:22587) |
| (R,R,R)-α-tocopherol (CHEBI:18145) has role EC 2.7.11.13 (protein kinase C) inhibitor (CHEBI:37700) |
| (R,R,R)-α-tocopherol (CHEBI:18145) has role immunomodulator (CHEBI:50846) |
| (R,R,R)-α-tocopherol (CHEBI:18145) has role micronutrient (CHEBI:27027) |
| (R,R,R)-α-tocopherol (CHEBI:18145) has role nutraceutical (CHEBI:50733) |
| (R,R,R)-α-tocopherol (CHEBI:18145) has role plant metabolite (CHEBI:76924) |
| (R,R,R)-α-tocopherol (CHEBI:18145) is a α-tocopherol (CHEBI:22470) |
| (R,R,R)-α-tocopherol (CHEBI:18145) is enantiomer of (S,S,S)-α-tocopherol (CHEBI:46430) |
| Incoming Relation(s) |
| 13-hydroxy-α-tocopherol (CHEBI:84962) has functional parent (R,R,R)-α-tocopherol (CHEBI:18145) |
| α-tocopheryloxyacetic acid (CHEBI:194185) has functional parent (R,R,R)-α-tocopherol (CHEBI:18145) |
| (S,S,S)-α-tocopherol (CHEBI:46430) is enantiomer of (R,R,R)-α-tocopherol (CHEBI:18145) |
| IUPAC Name |
|---|
| (2R)-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydro-2H-chromen-6-ol |
| Synonyms | Source |
|---|---|
| (2R)-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydro-2H-1-benzopyran-6-ol | IUPAC |
| (2R,4'R,8'R)-alpha-tocopherol | ChemIDplus |
| (2R,4'R,8'R)-α-tocopherol | ChemIDplus |
| (2R)-2,5,7,8-TETRAMETHYL-2-[(4R,8R)-4,8,12-TRIMETHYLTRIDECYL]CHROMAN-6-OL | PDBeChem |
| 5,7,8-trimethyltocol | ChemIDplus |
| (+)-alpha-tocopherol | ChemIDplus |
| UniProt Name | Source |
|---|---|
| (+)-α-tocopherol | UniProt |
| Manual Xrefs | Databases |
|---|---|
| 14265 | ChemSpider |
| 4280 | DrugCentral |
| Alpha-Tocopherol | Wikipedia |
| ALPHA-TOCOPHEROL | MetaCyc |
| C00007366 | KNApSAcK |
| C02477 | KEGG COMPOUND |
| DB00163 | DrugBank |
| FDB000565 | FooDB |
| HMDB0001893 | HMDB |
| LMPR02020001 | LIPID MAPS |
| VIV | PDBeChem |
| Citations |
|---|