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CHEBI:167680 - garomefrine hydrochloride

ChEBI IDCHEBI:167680
ChEBI Namegaromefrine hydrochloride
Stars
DefinitionA hydrochloride obtained by reaction of garomefrine with one equivalent of hydrochloric acid. It is a α1A adrenoreceptor agonist which was being developed for the treatment of urinary incontinence (now discontinued).
Last Modified15 March 2021
SubmitterAdnan
DownloadsMolfile
FormulaC9H13FN2O3S.HCl
Net Charge0
Average Mass284.740
Monoisotopic Mass284.03977
SMILESCS(=O)(=O)Nc1ccc(F)c([C@@H](O)CN)c1.Cl
InChIInChI=1S/C9H13FN2O3S.ClH/c1-16(14,15)12-6-2-3-8(10)7(4-6)9(13)5-11;/h2-4,9,12-13H,5,11H2,1H3;1H/t9-;/m0./s1
InChIKeyNYBZUGIMUSJVGU-FVGYRXGTSA-N
Roles Classification
Biological Role:
alpha-adrenergic agonist  An agent that selectively binds to and activates α-adrenergic receptors.
Applications:
nasal decongestant  A drug used to relieve nasal congestion in the upper respiratory tract.
alpha-adrenergic agonist  An agent that selectively binds to and activates α-adrenergic receptors.
ChEBI Ontology
Outgoing Relation(s)
garomefrine hydrochloride (CHEBI:167680) has part garomefrine(1+) (CHEBI:167679)
garomefrine hydrochloride (CHEBI:167680) has role nasal decongestant (CHEBI:77715)
garomefrine hydrochloride (CHEBI:167680) has role α-adrenergic agonist (CHEBI:35569)
garomefrine hydrochloride (CHEBI:167680) is a hydrochloride (CHEBI:36807)
IUPAC Name 
N-{3-[(1R)-2-amino-1-hydroxyethyl]-4-fluorophenyl}methanesulfonamide hydrochloride
Synonyms  Source
(2R)-2-{2-fluoro-5-[(methylsulfonyl)amino]phenyl}-2-hydroxyethanaminium chlorideIUPAC
PNO-49BChemIDplus
(−)-garomefrine hydrochlorideChemIDplus
ABT-232ChemIDplus
garomefrine monohydrochlorideChemIDplus
garomefrin hydrochlorideKEGG DRUG
Manual XrefsDatabases
D09784KEGG DRUG
8014482ChemSpider
Registry NumbersSources
CAS:137431-04-0ChemIDplus
Citations