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CHEBI:16347 - (R)-carnitine
| Formula | C7H15NO3 |
| Net Charge | 0 |
| Average Mass | 161.201 |
| Monoisotopic Mass | 161.10519 |
| SMILES | C[N+](C)(C)C[C@H](O)CC(=O)[O-] |
| InChI | InChI=1S/C7H15NO3/c1-8(2,3)5-6(9)4-7(10)11/h6,9H,4-5H2,1-3H3/t6-/m1/s1 |
| InChIKey | PHIQHXFUZVPYII-ZCFIWIBFSA-N |
| Species of Metabolite | Component | Source | Comments |
|---|---|---|---|
| Homo sapiens (ncbitaxon:9606) | |||
| - | DOI (10.1038/nbt.2488) | ||
| blood serum (BTO:0000133) | MetaboLights (MTBLS90) | ||
| Saccharomyces cerevisiae (ncbitaxon:4932) | - | PubMed (24678285) | Source: yeast.sf.net |
| Roles Classification |
|---|
| Biological Roles: | Saccharomyces cerevisiae metabolite Any fungal metabolite produced during a metabolic reaction in Baker's yeast (Saccharomyces cerevisiae ). anti-HIV agent An antiviral agent that destroys or inhibits the replication of the human immunodeficiency virus. water-soluble vitamin (role) Any vitamin that dissolves in water and readily absorbed into tissues for immediate use. Unlike the fat-soluble vitamins, they are not stored in the body and need to be replenished regularly in the diet and will rarely accumulate to toxic levels since they are quickly excreted from the body via urine. antiviral agent A substance that destroys or inhibits replication of viruses. immunosuppressive agent An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response. antibacterial agent A substance (or active part thereof) that kills or slows the growth of bacteria. human metabolite Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens). mouse metabolite Any mammalian metabolite produced during a metabolic reaction in a mouse (Mus musculus). |
| Applications: | antirheumatic drug A drug used to treat rheumatoid arthritis. antilipemic drug A substance used to treat hyperlipidemia (an excess of lipids in the blood). anti-asthmatic agent Any compound that has anti-asthmatic effects. renoprotective agent Any compound that is able to prevent damage to the kidneys. antidote Any protective agent counteracting or neutralizing the action of poisons. hypoglycemic agent A drug which lowers the blood glucose level. cardiovascular drug A drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume. immunosuppressive agent An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response. nutraceutical A product in capsule, tablet or liquid form that provide essential nutrients, such as a vitamin, an essential mineral, a protein, an herb, or similar nutritional substance. nootropic agent Any compound that improves mental functions such as cognition, memory, intelligence, motivation, attention, and concentration. antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. anti-arrhythmia drug A drug used for the treatment or prevention of cardiac arrhythmias. Anti-arrhythmia drugs may affect the polarisation-repolarisation phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibres. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| (R)-carnitine (CHEBI:16347) has role Saccharomyces cerevisiae metabolite (CHEBI:75772) |
| (R)-carnitine (CHEBI:16347) has role anti-arrhythmia drug (CHEBI:38070) |
| (R)-carnitine (CHEBI:16347) has role anti-asthmatic agent (CHEBI:65023) |
| (R)-carnitine (CHEBI:16347) has role anti-HIV agent (CHEBI:64946) |
| (R)-carnitine (CHEBI:16347) has role antibacterial agent (CHEBI:33282) |
| (R)-carnitine (CHEBI:16347) has role antidote (CHEBI:50247) |
| (R)-carnitine (CHEBI:16347) has role antilipemic drug (CHEBI:35679) |
| (R)-carnitine (CHEBI:16347) has role antineoplastic agent (CHEBI:35610) |
| (R)-carnitine (CHEBI:16347) has role antirheumatic drug (CHEBI:35842) |
| (R)-carnitine (CHEBI:16347) has role antiviral agent (CHEBI:22587) |
| (R)-carnitine (CHEBI:16347) has role cardiovascular drug (CHEBI:35554) |
| (R)-carnitine (CHEBI:16347) has role hypoglycemic agent (CHEBI:35526) |
| (R)-carnitine (CHEBI:16347) has role immunosuppressive agent (CHEBI:35705) |
| (R)-carnitine (CHEBI:16347) has role nootropic agent (CHEBI:66980) |
| (R)-carnitine (CHEBI:16347) has role nutraceutical (CHEBI:50733) |
| (R)-carnitine (CHEBI:16347) has role renoprotective agent (CHEBI:231911) |
| (R)-carnitine (CHEBI:16347) has role water-soluble vitamin (role) (CHEBI:27314) |
| (R)-carnitine (CHEBI:16347) is a carnitine (CHEBI:17126) |
| (R)-carnitine (CHEBI:16347) is conjugate base of (R)-carnitinium (CHEBI:39547) |
| (R)-carnitine (CHEBI:16347) is enantiomer of (S)-carnitine (CHEBI:11060) |
| Incoming Relation(s) |
| (R)-carnitinamide (CHEBI:17159) has functional parent (R)-carnitine (CHEBI:16347) |
| (3R)-4-(dimethylammonio)-3-hydroxybutanoate (CHEBI:183234) has functional parent (R)-carnitine (CHEBI:16347) |
| O-acyl-L-carnitine (CHEBI:75659) has functional parent (R)-carnitine (CHEBI:16347) |
| (R)-carnitinium (CHEBI:39547) is conjugate acid of (R)-carnitine (CHEBI:16347) |
| (S)-carnitine (CHEBI:11060) is enantiomer of (R)-carnitine (CHEBI:16347) |
| IUPAC Name |
|---|
| (3R)-3-hydroxy-4-(trimethylammonio)butanoate |
| INN | Source |
|---|---|
| levocarnitina | WHO MedNet |
| Synonyms | Source |
|---|---|
| 3-Carboxy-2-hydroxy-N,N,N-trimethyl-1-propanaminium hydroxide, inner salt | KEGG COMPOUND |
| (-)-Carnitine | ChemIDplus |
| Carnitine | ChemIDplus |
| (-)-L-Carnitine | ChemIDplus |
| L-Carnitine | KEGG COMPOUND |
| levocarnitine | ChEMBL |
| Brand Names | Source |
|---|---|
| Carnicor | ChEBI |
| Carnitene | ChEBI |
| Carnitor | DrugBank |
| Carnitor sf | ChEMBL |
| Karnitin | DrugBank |
| UniProt Name | Source |
|---|---|
| (R)-carnitine | UniProt |
| Citations |
|---|