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CHEBI:156351 - gougerotin

ChEBI IDCHEBI:156351
ChEBI Namegougerotin
Stars
DefinitionA peptidyl nucleoside antibiotic which functions as a specific inhibitor of protein synthesis by binding ribosomal peptidyl transferase.
Last Modified16 October 2023
SubmitterMartin Larralde
DownloadsMolfile
FormulaC16H25N7O8
Net Charge0
Average Mass443.417
Monoisotopic Mass443.17646
SMILESCNCC(=O)N[C@H](CO)C(=O)N[C@H]1[C@H](O)[C@@H](O)[C@H](n2ccc(N)nc2=O)O[C@@H]1C(N)=O
InChIInChI=1S/C16H25N7O8/c1-19-4-8(25)20-6(5-24)14(29)22-9-10(26)11(27)15(31-12(9)13(18)28)23-3-2-7(17)21-16(23)30/h2-3,6,9-12,15,19,24,26-27H,4-5H2,1H3,(H2,18,28)(H,20,25)(H,22,29)(H2,17,21,30)/t6-,9+,10+,11-,12+,15-/m1/s1
InChIKeyAMNAZJFEONUVTD-QJHHURCWSA-N
Wikipedia
Species of MetaboliteComponentSourceComments
Streptomyces graminearus (ncbitaxon:284030) - PubMed (23352137)
Roles Classification
Chemical Role:
Bronsted base  A molecular entity capable of accepting a hydron from a donor (Brønsted acid).
Biological Roles:
bacterial metabolite  Any prokaryotic metabolite produced during a metabolic reaction in bacteria.
protein synthesis inhibitor  A compound, usually an anti-bacterial agent or a toxin, which inhibits the synthesis of a protein.
antimicrobial agent  A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans.
fungicide  A substance used to destroy fungal pests.
EC 2.3.2.* (aminoacyltransferase) inhibitor  An EC 2.3.* (acyltransferase) inhibitor that interferes with the action of any aminoacyltransferase (EC 2.3.2.*).
Application:
fungicide  A substance used to destroy fungal pests.
ChEBI Ontology
Outgoing Relation(s)
gougerotin (CHEBI:156351) has functional parent cytosine (CHEBI:16040)
gougerotin (CHEBI:156351) has functional parent serine (CHEBI:17822)
gougerotin (CHEBI:156351) has role antimicrobial agent (CHEBI:33281)
gougerotin (CHEBI:156351) has role bacterial metabolite (CHEBI:76969)
gougerotin (CHEBI:156351) has role EC 2.3.2.* (aminoacyltransferase) inhibitor (CHEBI:76877)
gougerotin (CHEBI:156351) has role fungicide (CHEBI:24127)
gougerotin (CHEBI:156351) has role nucleoside antibiotic (CHEBI:25605)
gougerotin (CHEBI:156351) has role protein synthesis inhibitor (CHEBI:48001)
gougerotin (CHEBI:156351) is a oligopeptide (CHEBI:25676)
gougerotin (CHEBI:156351) is a pyrimidine nucleoside (CHEBI:26440)
gougerotin (CHEBI:156351) is a triol (CHEBI:27136)
Synonyms  Source
aspiculamycinKNApSAcK
asteromycinKNApSAcK
quingfengmycinSUBMITTER
Manual XrefsDatabases
GougerotinWikipedia
C00018700KNApSAcK
Registry NumbersSources
CAS:2096-42-6ChemIDplus
Citations