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CHEBI:156315 - erdasporine C

ChEBI IDCHEBI:156315
ChEBI Nameerdasporine C
Stars
DefinitionAn organic heterohexacyclic compound that is 6,7,12,13-tetrahydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazole in which the hydrogens at positions 5 and 7 are substituted by a methoxycarbonyl and oxo groups, respectively. It is synthesized by a gene cluster found in environmental DNA and exhibits cytotoxic activity against human HCT116 cancer cells and Staphylococcus aureus.
Last Modified18 August 2020
SubmitterMartin Larralde
DownloadsMolfile
FormulaC22H15N3O3
Net Charge0
Average Mass369.380
Monoisotopic Mass369.11134
SMILESCOC(=O)C1NC(=O)c2c1c1c3ccccc3nc1c1nc3ccccc3c21
InChIInChI=1S/C22H15N3O3/c1-28-22(27)20-16-14-10-6-2-4-8-12(10)23-18(14)19-15(17(16)21(26)25-20)11-7-3-5-9-13(11)24-19/h2-9,20,23-24H,1H3,(H,25,26)
InChIKeyDOZODIABNANYHJ-UHFFFAOYSA-N
Roles Classification
Chemical Role:
Bronsted base  A molecular entity capable of accepting a hydron from a donor (Brønsted acid).
Biological Roles:
toxin  Poisonous substance produced by a biological organism such as a microbe, animal or plant.
antibacterial agent  A substance (or active part thereof) that kills or slows the growth of bacteria.
metabolite  Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
Application:
antineoplastic agent  A substance that inhibits or prevents the proliferation of neoplasms.
ChEBI Ontology
Outgoing Relation(s)
erdasporine C (CHEBI:156315) has functional parent erdasporine B (CHEBI:156314)
erdasporine C (CHEBI:156315) has role antibacterial agent (CHEBI:33282)
erdasporine C (CHEBI:156315) has role antineoplastic agent (CHEBI:35610)
erdasporine C (CHEBI:156315) has role toxin (CHEBI:27026)
erdasporine C (CHEBI:156315) is a indolocarbazole alkaloid (CHEBI:37697)
erdasporine C (CHEBI:156315) is a methyl ester (CHEBI:25248)
erdasporine C (CHEBI:156315) is a organic heterohexacyclic compound (CHEBI:51914)
erdasporine C (CHEBI:156315) is a secondary amino compound (CHEBI:50995)
IUPAC Name 
methyl 7-oxo-6,7,12,13-tetrahydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazole-5-carboxylate
Synonym  Source
methyl 14-oxo-3,13,23-triazahexacyclo[14.7.0.02,10.04,9.011,15.017,22]tricosa-1,4,6,8,10,15,17,19,21-nonaene-12-carboxylateIUPAC
Citations