polyhexamethylene biguanide hydrochloride (CHEBI:149534)

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CHEBI:149534 - polyhexamethylene biguanide hydrochloride

ChEBI ID	CHEBI:149534
ChEBI Name	polyhexamethylene biguanide hydrochloride
Stars
Definition	A hydrochloride salt of polyhexamethylene biguanide. It is a broad spectrum and fast acting bactericide which is used for the formulation of disinfectants and sanitisers.
Last Modified	22 April 2020
Submitter	Adnan
Downloads	Molfile

Formula	(C8H17N5)n.(HCl)m
Net Charge	0
Average Mass	219.720
Monoisotopic Mass	219.12507
SMILES	CCCCCCNC(=N)NC(=N)N.Cl

Roles Classification

Biological Roles:

antifungal agent An antimicrobial agent that destroys fungi by suppressing their ability to grow or reproduce.

antibacterial agent A substance (or active part thereof) that kills or slows the growth of bacteria.

disinfectant An antimicrobial agent that is applied to non-living objects to destroy harmful microorganisms or to inhibit their activity.

Applications:

dermatologic drug A drug used to treat or prevent skin disorders or for the routine care of skin.

ophthalmology drug Any compound used for the treatment of eye conditions or eye diseases.

antiseptic drug A substance used locally on humans and other animals to destroy harmful microorganisms or to inhibit their activity (cf. disinfectants, which destroy microorganisms found on non-living objects, and antibiotics, which can be transported through the lymphatic system to destroy bacteria within the body).

ChEBI Ontology

Outgoing Relation(s)
	polyhexamethylene biguanide hydrochloride (CHEBI:149534) has part polyhexamethylene biguanide(2+) (CHEBI:149538)
	polyhexamethylene biguanide hydrochloride (CHEBI:149534) has role antibacterial agent (CHEBI:33282)
	polyhexamethylene biguanide hydrochloride (CHEBI:149534) has role antifungal agent (CHEBI:35718)
	polyhexamethylene biguanide hydrochloride (CHEBI:149534) has role antiseptic drug (CHEBI:48218)
	polyhexamethylene biguanide hydrochloride (CHEBI:149534) has role dermatologic drug (CHEBI:50177)
	polyhexamethylene biguanide hydrochloride (CHEBI:149534) has role disinfectant (CHEBI:48219)
	polyhexamethylene biguanide hydrochloride (CHEBI:149534) has role ophthalmology drug (CHEBI:66981)
	polyhexamethylene biguanide hydrochloride (CHEBI:149534) is a hydrochloride (CHEBI:36807)

Synonyms	Source
hexamethylenediamine polymer hydrochloride	ChEBI
PHMB-HCl	ChEBI
PHMB hydrochloride	ChEBI
polihexanide HCl	DrugBank
polihexanide hydrochloride	DrugBank
poly(hexamethylenebiguanide) hydrochloride	ChEBI

Brand Names	Source
Cosmocil	ChemIDplus
Cosmoquil CQ	ChemIDplus
poly(hexamethylene) biguanide hydrochloride	ChemIDplus
Prontoderm	ChemIDplus
Prontosan	ChemIDplus
Reputex 20	ChemIDplus

Manual Xrefs	Databases
D08399	KEGG DRUG
DBSALT002168	DrugBank

Registry Numbers	Sources
CAS:32289-58-0	ChemIDplus

Citations