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CHEBI:143343 - 5-(2-chlorophenyl)-7-(dihydroxyamino)-1,3-dihydro-1,4-benzodiazepin-2-one

ChEBI IDCHEBI:143343
ChEBI Name5-(2-chlorophenyl)-7-(dihydroxyamino)-1,3-dihydro-1,4-benzodiazepin-2-one
Stars
Submittermwilliams
DownloadsMolfile
FormulaC15H12ClN3O3
Net Charge0
Average Mass317.732
Monoisotopic Mass317.05672
SMILESO=C1CN=C(c2ccccc2Cl)c2cc(N(O)O)ccc2N1
InChIInChI=1S/C15H12ClN3O3/c16-12-4-2-1-3-10(12)15-11-7-9(19(21)22)5-6-13(11)18-14(20)8-17-15/h1-7,21-22H,8H2,(H,18,20)
InChIKeyQKPRGUMFCHDCOK-UHFFFAOYSA-N
Roles Classification
Biological Role:
GABA modulator  A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
Application:
GABA modulator  A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
ChEBI Ontology
Outgoing Relation(s)
5-(2-chlorophenyl)-7-(dihydroxyamino)-1,3-dihydro-1,4-benzodiazepin-2-one (CHEBI:143343) is a 1,4-benzodiazepinone (CHEBI:35500)
5-(2-chlorophenyl)-7-(dihydroxyamino)-1,3-dihydro-1,4-benzodiazepin-2-one (CHEBI:143343) is a monochlorobenzenes (CHEBI:83403)