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CHEBI:135752 - tafenoquine
| ChEBI ID | CHEBI:135752 |
| ChEBI Name | tafenoquine |
| Stars | |
| Definition | A racemate comprising equimolar amounts of (R)- and (S)-tafenoquine. |
| Last Modified | 29 August 2018 |
| Formula | C24H28F3N3O3 |
| Net Charge | 0 |
| Average Mass | 463.494 |
| Monoisotopic Mass | 463.20828 |
| Wikipedia |
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| Roles Classification |
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| Biological Roles: | antimalarial A drug used in the treatment of malaria. Antimalarials are usually classified on the basis of their action against Plasmodia at different stages in their life cycle in the human. apoptosis inducer Any substance that induces the process of apoptosis (programmed cell death) in multi-celled organisms. trypanocidal drug A drug used to treat or prevent infections caused by protozoal organisms belonging to the suborder Trypanosomatida. antileishmanial agent An antiprotozoal drug used to treat or prevent infections caused by protozoan parasites that belong to the genus Leishmania. |
| Applications: | antimalarial A drug used in the treatment of malaria. Antimalarials are usually classified on the basis of their action against Plasmodia at different stages in their life cycle in the human. trypanocidal drug A drug used to treat or prevent infections caused by protozoal organisms belonging to the suborder Trypanosomatida. antileishmanial agent An antiprotozoal drug used to treat or prevent infections caused by protozoan parasites that belong to the genus Leishmania. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| tafenoquine (CHEBI:135752) has part (R)-tafenoquine (CHEBI:141488) |
| tafenoquine (CHEBI:135752) has part (S)-tafenoquine (CHEBI:141489) |
| tafenoquine (CHEBI:135752) has role antileishmanial agent (CHEBI:70868) |
| tafenoquine (CHEBI:135752) has role antimalarial (CHEBI:38068) |
| tafenoquine (CHEBI:135752) has role apoptosis inducer (CHEBI:68495) |
| tafenoquine (CHEBI:135752) has role trypanocidal drug (CHEBI:36335) |
| tafenoquine (CHEBI:135752) is a racemate (CHEBI:60911) |
| IUPAC Name |
|---|
| rac-N4-{2,6-dimethoxy-4-methyl-5-[3-(trifluoromethyl)phenoxy]quinolin-8-yl}pentane-1,4-diamine |
| INNs | Source |
|---|---|
| tafenoquina | WHO MedNet |
| tafénoquine | WHO MedNet |
| tafenoquinum | ChEBI |
| tafenoquine | ChemIDplus |
| Synonyms | Source |
|---|---|
| etaquine | ChEBI |
| WR238605 | ChEBI |
| WR 238,605 | ChEBI |
| Brand Names | Source |
|---|---|
| Krintafel | ChEBI |
| Arakoda | ChEBI |
| Manual Xrefs | Databases |
|---|---|
| 3578 | DrugCentral |
| Tafenoquine | Wikipedia |
| D10490 | KEGG DRUG |
| DB06608 | DrugBank |
| Registry Numbers | Sources |
|---|---|
| Reaxys:6493037 | Reaxys |
| CAS:106635-80-7 | DrugCentral |
| CAS:106635-80-7 | ChemIDplus |
| Citations |
|---|