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CHEBI:135538 - propyphenazone

ChEBI IDCHEBI:135538
ChEBI Namepropyphenazone
Stars
DefinitionA pyrazolone derivative that is antipyrine substituted at C-4 by an isopropyl group.
Secondary ChEBI IDCHEBI:31732
Last Modified6 March 2017
DownloadsMolfile
FormulaC14H18N2O
Net Charge0
Average Mass230.311
Monoisotopic Mass230.14191
SMILESCc1c(C(C)C)c(=O)n(-c2ccccc2)n1C
InChIInChI=1S/C14H18N2O/c1-10(2)13-11(3)15(4)16(14(13)17)12-8-6-5-7-9-12/h5-10H,1-4H3
InChIKeyPXWLVJLKJGVOKE-UHFFFAOYSA-N
Wikipedia
Roles Classification
Biological Role:
non-narcotic analgesic  A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors.
Applications:
peripheral nervous system drug  A drug that acts principally at one or more sites within the peripheral neuroeffector systems, the autonomic system, and motor nerve-skeletal system.
non-narcotic analgesic  A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors.
non-steroidal anti-inflammatory drug  An anti-inflammatory drug that is not a steroid. In addition to anti-inflammatory actions, non-steroidal anti-inflammatory drugs have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins.
ChEBI Ontology
Outgoing Relation(s)
propyphenazone (CHEBI:135538) has functional parent antipyrine (CHEBI:31225)
propyphenazone (CHEBI:135538) has role non-narcotic analgesic (CHEBI:35481)
propyphenazone (CHEBI:135538) has role non-steroidal anti-inflammatory drug (CHEBI:35475)
propyphenazone (CHEBI:135538) has role peripheral nervous system drug (CHEBI:49110)
propyphenazone (CHEBI:135538) is a pyrazolone (CHEBI:83328)
IUPAC Name 
1,5-dimethyl-2-phenyl-4-(propan-2-yl)-1,2-dihydro-3H-pyrazol-3-one
INNs  Source
propyphenazoneChemIDplus
propifenazonaChemIDplus
propyphenazonumChemIDplus
Synonyms  Source
4-Isopropyl-1,5-dimethyl-2-phenyl-1,2-dihydro-pyrazol-3-oneChEMBL
1-Phenyl-2,3-dimethyl-4-isopropyl-3-pyrazolin-5-oneChemIDplus
1-Phenyl-2,3-dimethyl-4-isopropylpyrazol-5-oneChemIDplus
4-IsopropylantipyrineChemIDplus
IsopropylantipyrineChemIDplus
IsopropylphenazoneChemIDplus
Manual XrefsDatabases
D01380KEGG DRUG
PropyphenazoneWikipedia
2309DrugCentral
Registry NumbersSources
Reaxys:204533Reaxys
CAS:479-92-5ChemIDplus
Citations