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CHEBI:134722 - favipiravir

ChEBI IDCHEBI:134722
ChEBI Namefavipiravir
Stars
DefinitionA member of the class of pyrazines that is pyrazine substituted by aminocarbonyl, hydroxy and fluoro groups at positions 2, 3 and 6, respectively. It is an anti-viral agent that inhibits RNA-dependent RNA polymerase of several RNA viruses and is approved for the treatment of influenza in Japan.
Last Modified26 April 2021
DownloadsMolfile
FormulaC5H4FN3O2
Net Charge0
Average Mass157.104
Monoisotopic Mass157.02875
SMILESNC(=O)c1nc(F)cnc1O
InChIInChI=1S/C5H4FN3O2/c6-2-1-8-5(11)3(9-2)4(7)10/h1H,(H2,7,10)(H,8,11)
InChIKeyZCGNOVWYSGBHAU-UHFFFAOYSA-N
Wikipedia
Roles Classification
Biological Roles:
antiviral drug  A substance used in the prophylaxis or therapy of virus diseases.
EC 2.7.7.48 (RNA-directed RNA polymerase) inhibitor  A DNA polymerase inhibitor that interferes with the action of a RNA-directed RNA polymerase (EC 2.7.7.48).
anticoronaviral agent  Any antiviral agent which inhibits the activity of coronaviruses.
Application:
antiviral drug  A substance used in the prophylaxis or therapy of virus diseases.
ChEBI Ontology
Outgoing Relation(s)
favipiravir (CHEBI:134722) has role anticoronaviral agent (CHEBI:149553)
favipiravir (CHEBI:134722) has role antiviral drug (CHEBI:36044)
favipiravir (CHEBI:134722) has role EC 2.7.7.48 (RNA-directed RNA polymerase) inhibitor (CHEBI:170010)
favipiravir (CHEBI:134722) is a hydroxypyrazine (CHEBI:71633)
favipiravir (CHEBI:134722) is a organofluorine compound (CHEBI:37143)
favipiravir (CHEBI:134722) is a primary carboxamide (CHEBI:140324)
Incoming Relation(s)
favipiravir-RTP (CHEBI:170009) has functional parent favipiravir (CHEBI:134722)
IUPAC Name 
6-fluoro-3-hydroxypyrazine-2-carboxamide
INNs  Source
favipiravirWHO MedNet
favipiravirWHO MedNet
favipiravirumWHO MedNet
favipiravirWHO MedNet
Synonyms  Source
T-705ChemIDplus
T 705ChemIDplus
T705ChemIDplus
6-fluoro-3-hydroxy-2-pyrazinecarboxamideChemIDplus
fapilavirDrugBank
Brand Names  Source
AviganKEGG DRUG
AvifavirChEBI
AreplivirChEBI
FavipiraChEBI
FavilavirChEBI
Manual XrefsDatabases
4887DrugCentral
DB12466DrugBank
D09537KEGG DRUG
FavipiravirWikipedia
431002ChemSpider
Registry NumbersSources
Reaxys:9697246Reaxys
CAS:259793-96-9ChemIDplus
Citations