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CHEBI:126237 - enprofylline

ChEBI IDCHEBI:126237
ChEBI Nameenprofylline
Stars
DefinitionXanthine bearing a propyl substituent at position 3. A bronchodilator, it is used for the symptomatic treatment of asthma and chronic obstructive pulmonary disease, and in the management of cerebrovascular insufficiency, sickle cell disease, and diabetic neuropathy.
Secondary ChEBI IDCHEBI:665397
Last Modified27 November 2019
DownloadsMolfile
FormulaC8H10N4O2
Net Charge0
Average Mass194.194
Monoisotopic Mass194.08038
SMILESCCCn1c(=O)nc(=O)c2ncnc21
InChIInChI=1S/C8H10N4O2/c1-2-3-12-6-5(9-4-10-6)7(13)11-8(12)14/h4H,2-3H2,1H3,(H,9,10)(H,11,13,14)
InChIKeySIQPXVQCUCHWDI-UHFFFAOYSA-N
Roles Classification
Applications:
bronchodilator agent  An agent that causes an increase in the expansion of a bronchus or bronchial tubes.
anti-arrhythmia drug  A drug used for the treatment or prevention of cardiac arrhythmias. Anti-arrhythmia drugs may affect the polarisation-repolarisation phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibres.
anti-asthmatic drug  A drug used to treat asthma.
non-steroidal anti-inflammatory drug  An anti-inflammatory drug that is not a steroid. In addition to anti-inflammatory actions, non-steroidal anti-inflammatory drugs have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins.
ChEBI Ontology
Outgoing Relation(s)
enprofylline (CHEBI:126237) has role anti-arrhythmia drug (CHEBI:38070)
enprofylline (CHEBI:126237) has role anti-asthmatic drug (CHEBI:49167)
enprofylline (CHEBI:126237) has role bronchodilator agent (CHEBI:35523)
enprofylline (CHEBI:126237) has role non-steroidal anti-inflammatory drug (CHEBI:35475)
enprofylline (CHEBI:126237) is a oxopurine (CHEBI:25810)
Incoming Relation(s)
1-methyl-3-propyl-7H-xanthine (CHEBI:145517) has functional parent enprofylline (CHEBI:126237)
IUPAC Name 
3-propyl-3,7-dihydro-1H-purine-2,6-dione
INNs  Source
enprofyllineChemIDplus
enprofyllinumChemIDplus
enprofilinaChemIDplus
Synonyms  Source
3-Propyl-3,7-dihydro-purine-2,6-dioneChEMBL
EnprofyllineChEMBL
3-propylxanthineChemIDplus
3,7-dihydro-3-propyl-1H-purine-2,6-dioneChemIDplus
3-n-propylxanthineDrugBank
Manual XrefsDatabases
DB00824DrugBank
D04006KEGG DRUG
1015DrugCentral
Registry NumbersSources
Beilstein:4189165Beilstein
CAS:41078-02-8KEGG DRUG
CAS:41078-02-8ChemIDplus