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CHEBI:126237 - enprofylline

Default Structure
ChEBI IDCHEBI:126237
ChEBI Nameenprofylline
Stars
DefinitionXanthine bearing a propyl substituent at position 3. A bronchodilator, it is used for the symptomatic treatment of asthma and chronic obstructive pulmonary disease, and in the management of cerebrovascular insufficiency, sickle cell disease, and diabetic neuropathy.
Secondary ChEBI IDCHEBI:665397
Last Modified27 November 2019
DownloadsMolfile
FormulaC8H10N4O2
Net Charge0
Average Mass194.194
Monoisotopic Mass194.08038
SMILESCCCn1c(=O)nc(=O)c2ncnc21
InChIInChI=1S/C8H10N4O2/c1-2-3-12-6-5(9-4-10-6)7(13)11-8(12)14/h4H,2-3H2,1H3,(H,9,10)(H,11,13,14)
InChIKeySIQPXVQCUCHWDI-UHFFFAOYSA-N
Roles Classification
Applications:
non-steroidal anti-inflammatory drug  An anti-inflammatory drug that is not a steroid. In addition to anti-inflammatory actions, non-steroidal anti-inflammatory drugs have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins.
anti-arrhythmia drug  A drug used for the treatment or prevention of cardiac arrhythmias. Anti-arrhythmia drugs may affect the polarisation-repolarisation phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibres.
bronchodilator agent  An agent that causes an increase in the expansion of a bronchus or bronchial tubes.
anti-asthmatic drug  A drug used to treat asthma.
ChEBI Ontology
Outgoing Relation(s)
enprofylline (CHEBI:126237) has role anti-arrhythmia drug (CHEBI:38070)
enprofylline (CHEBI:126237) has role anti-asthmatic drug (CHEBI:49167)
enprofylline (CHEBI:126237) has role bronchodilator agent (CHEBI:35523)
enprofylline (CHEBI:126237) has role non-steroidal anti-inflammatory drug (CHEBI:35475)
enprofylline (CHEBI:126237) is a organic molecular entity (CHEBI:50860)
enprofylline (CHEBI:126237) is a oxopurine (CHEBI:25810)
Incoming Relation(s)
1-methyl-3-propyl-7H-xanthine (CHEBI:145517) has functional parent enprofylline (CHEBI:126237)
IUPAC Name 
3-propyl-3,7-dihydro-1H-purine-2,6-dione
INNs  Source
enprofilinaChemIDplus
enprofyllineChemIDplus
enprofyllinumChemIDplus
Synonyms  Source
3,7-dihydro-3-propyl-1H-purine-2,6-dioneChemIDplus
3-n-propylxanthineDrugBank
3-Propyl-3,7-dihydro-purine-2,6-dioneChEMBL
3-propylxanthineChemIDplus
D 4028ChEMBL
D-4028ChEMBL
Manual XrefsDatabases
1015DrugCentral
D04006KEGG DRUG
DB00824DrugBank
Registry NumbersSources
Beilstein:4189165Beilstein
CAS:41078-02-8KEGG DRUG
CAS:41078-02-8ChemIDplus
Citations